Results 51 to 60 of about 23,744 (306)

Genetic Identification Of Ground Ice By Petrographic Method

Geography, Environment, Sustainability, 2021
The advantages and limitations of the petrography method and the relevance of its use for the study of natural ice are reviewed in the present work. The petrographic method of ground ice study is often used for solving paleogeographic issues.
Yana V. Tikhonravova, Viktor V. Rogov, Elena A. Slagoda   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Anatomy and origin of authochthonous late Pleistocene forced regression deposits, east Coromandel inner shelf, New Zealand: implications for the development and definition of the regressive systems tract [PDF]

, 2004
High-resolution seismic reflection data from the east Coromandel coast, New Zealand, provide details of the sequence stratigraphy beneath an autochthonous, wave dominated inner shelf margin during the late Quaternary (0-140 ka). Since c.
Bard E., Bard E., Bond G., Bradshaw B. E., Bradshaw B. E., Browne G. H., Chappell J., Chiocci F. L., Dansgaard W., Davis R. A., Emery D., Hart B. S., Haywick D. W., Hernández‐Molina F. J., Hunt D., Hunt D., Kitamura A., Kolla V., Kolla V., Marks G. P., Marshall J. F., Martinson D. G., Mellere D., Mitchum R. M., Morton R. A., Naish T., Nummedal D., Plint A. G., Plint A. G., Plint A. G., Plint A. G., Pomar L., Posamentier H. W., Posamentier H. W., Posamentier H. W., Roy P. S., Roy P. S., Saul G., Schofield J. C., Shackleton N. J., Tesson M. R., Thom B. G., Thom B. G., Thom B. G., Thrasher G. P., Trincardi F., Vail P. R., Van Wagoner J. C., Van Wagoner J. C., Wright I. C., Wright I. C.   +50 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Nonlinear thermal and moisture response of ice-wedge polygons to permafrost disturbance increases heterogeneity of high Arctic wetland [PDF]

Biogeosciences, 2016
Low-center polygonal terrains with gentle sloping surfaces and lowlands in the high Arctic have a potential to retain water in the lower central portion of ice-wedge polygons and are considered high-latitude wetlands.
E. Godin, D. Fortier, E. Lévesque
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

An estimate of ice wedge volume for a High Arctic polar desert environment, Fosheim Peninsula, Ellesmere Island [PDF]

The Cryosphere, 2018
Quantifying ground-ice volume on a regional scale is necessary to assess the vulnerability of permafrost landscapes to thaw-induced disturbance like terrain subsidence and to quantify potential carbon release. Ice wedges (IWs) are a ubiquitous ground-ice
C. Bernard-Grand'Maison, W. Pollard
doaj   +1 more source

Quantum Indistinguishability in Chemical Reactions [PDF]

, 2017
Quantum indistinguishability plays a crucial role in many low-energy physical phenomena, from quantum fluids to molecular spectroscopy. It is, however, typically ignored in most high temperature processes, particularly for ionic coordinates, implicitly ...
Fisher, Matthew P. A., Radzihovsky, Leo
core   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source