Results 91 to 100 of about 2,850 (288)

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

State College Times, November 7, 1933 [PDF]

, 1933
Volume 22, Issue 27https://scholarworks.sjsu.edu/spartandaily/12921/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Impact of rain on transmission lines’ ampacity: Scotland as a case study [PDF]

, 2018
Abdael Baset, Abdallah, Farokhi, Shahab, Farrag, M. Emad   +2 more
core   +1 more source

A comparative analysis of the decoupling effects in a magnetic forming beryllium coil assembly [PDF]

Digital computer for determining currents and forces in magnetic forming beryllium coil ...
Bennett, L. D., Rogers, J. W., Wier, D. D.   +2 more
core   +1 more source

Focal Cooling for Drug-Resistant Epilepsy: A Review. [PDF]

JAMA Neurol, 2022
Niesvizky-Kogan I, Bass M, Goldenholz SR, Goldenholz DM.   +3 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Electro-mechanical de-icer modeling with aeronautics application

, 2016
International audienceThe development of a multi physics model, for a new electro-mechanical de-icing solution, is presented in thisarticle. The technology proposed by aeronautics industry resides in the principles of Laplace forces and plate elastic ...
Clavel, Edith, ESTOPIER CASTILLO, Melissa, Galopin, Nicolas, LE GARREC, Stephane, NGUYEN, Trung, Wurtz, Frédéric   +5 more
core   +1 more source

Study on Temperature Characteristics of Ice-covered Conductors during Ice-melting [PDF]

Proceedings of the 2016 6th International Conference on Advanced Design and Manufacturing Engineering (ICADME 2016), 2016
Wenhao Li, Tingbin Li, Wei Zhong, Tianxiang Hu, Shoubao Liu, Bin He, Daxing Wang   +6 more
openaire   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source