Results 61 to 70 of about 2,850 (288)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Electro-impulse de-icing testing analysis and design [PDF]
Electro-Impulse De-Icing (EIDI) is a method of ice removal by sharp blows delivered by a transient electromagnetic field. Detailed results are given for studies of the electrodynamic phenomena.
Bernhart, W. D. +3 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Surface roughness due to residual ice in the use of low power deicing systems [PDF]
Thicknesses of residual ice are presented to provide information on surface contamination and associated roughness during deicing events. Data was obtained from low power ice protection systems tests conducted in the Icing Research Tunnel at NASA Lewis ...
Bond, Thomas H., Shin, Jaiwon
core +1 more source
Advances in AerodynamicsThe one-equation Spalart–Allmaras (SA) model is employed to close the Reynolds averaged Navier–Stokes equations (RANS equations), and research on turbulent numerical algorithm is carried out.
Shaokai Liao +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A Critical Review of the Measurement of Ice Adhesion to Solid Substrates [PDF]
Ice adhesion is an issue spanning a wide range of technical fields. In the aerospace industry, ice accretion has led to a large number of casualties and costs the industry billions of dollars every year.
Lian, Yongsheng, Work, Andrew H.
core +1 more source
Comparison of extensional and flexural modes for the design of piezoelectric ice protection systems [PDF]
, 2017 Many researches focus on piezoelectric ice protection systems with the objectives to develop light and low consumption electromechanical systems for de-icing.
Budinger, Marc +2 more
core +1 more source