Results 141 to 150 of about 35,107 (301)

Incremental cost-effectiveness ratios (ICER, in USD/QALY).

open access: yes
Incremental cost-effectiveness ratios (ICER, in USD/QALY).
Chanchai Charonpongsuntorn (18196364)   +7 more
core   +1 more source

Checkpoint‐Directed Glycoengineering Reprograms the Vascular Lumen for Siglec‐Mediated Immune Regulation

open access: yesAdvanced Science, EarlyView.
Checkpoint‐directed glycoengineering installs sialylated ligands on the donor vascular lumen during ex vivo preservation, creating a localized Siglec‐7/9‐engaging interface. The engineered glycocalyx suppresses immune‐cell activation, complement deposition, and microvascular injury in arterial and kidney allografts while preserving endothelial ...
Md Mohosin Rana   +19 more
wiley   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

open access: yesAdvanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo   +15 more
wiley   +1 more source

Hybrid Spring‐Coupled Broadband Energy Harvester Integrated with CuSCN Functionalized Triboelectric Vibration Sensor for Self‐Sustainable Vehicular IoTs

open access: yesAdvanced Science, EarlyView.
A self‐sustainable vehicular vibration and indoor environment monitoring IoT platform is developed which integrates a hybrid spring‐coupled broadband energy harvester with a machine learning‐assisted PAN‐CuSCN nanofiber triboelectric vibration sensor for subtle‐to‐wide‐range vibration detection and road/speed classification.
Trilochan Bhatta   +6 more
wiley   +1 more source

PNS174 INFLUENCING ICER: A REVIEW OF MANUFACTURER INVOLVEMENT IN ICER ASSESSMENTS [PDF]

open access: yesValue in Health, 2019
M. Atkinson   +4 more
openaire   +1 more source

CRISPR‐Scan: Cas13a Mismatch Tolerance Enabled Ultra‐Multiplexed Detection of Same‐Site Indels in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
Accurately detecting diverse same‐locus insertions or deletions (indels) remains challenging. This study reveals the mismatch‐tolerance profile of LwaCas13a and establishes CRISPR‐Scan, which uses a single crRNA to detect multiple same‐locus indels. The one‐pot assay detects nucleophosmin 1 (NPM1) mutant allele frequencies down to 0.01%, agrees with ...
Linlin Bai   +13 more
wiley   +1 more source

Improved Deformability of Co‐Free Medium Entropy Oxides by Controlled Entropy Destabilization

open access: yesAdvanced Science, EarlyView.
Controlled entropy destabilization activates defect‐mediated plasticity in Co‐free (CuMgNiZn)O by promoting pre‐existing Cu‐rich secondary phases that serve as defect sources. Temperature‐dependent dislocation activity evolves from limited motion at room temperature to extensive glide and stacking‐fault formation at 600 °C, enabling improved plasticity
Chang Liu   +10 more
wiley   +1 more source

Inducible cAMP Early Repressor Limits Glycolytic Programming in Regulatory T Cells and Supports Control of Inflammatory Colitis. [PDF]

open access: yesEur J Immunol
Lopez Krol A   +12 more
europepmc   +1 more source

Toward Rational Design of Aqueous Battery Membranes Beyond the Selectivity‐Conductivity Trade‐Off

open access: yesAdvanced Science, EarlyView.
This review examines sulfonated membranes for redox flow batteries. It focuses on proton transport mechanism, membrane design, performance limits, optimization strategies, and the pathway from molecular design to membrane manufacturing. ABSTRACT Electrochemical energy‐storage systems increasingly require membranes that can simultaneously deliver fast ...
Jinkang Liu   +13 more
wiley   +1 more source

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