Results 1 to 10 of about 74,894 (355)
A QALY is [still] a QALY is [still] a QALY? [PDF]
Despite clinical evidence of drug superiority, therapeutic modalities, like combination immunotherapy, are mostly considered cost-ineffective due to their high costs per life year(s) gained.
Hamideh Mahdiani +2 more
doaj +5 more sources
Abandoning Eugenics and the QALY
Should decision making in health care, notably in respect of the allocation of resources between individuals and disease states, rest on notions of the burden of disease and denial of care as assessed by societal evaluations or on the extent to which the
Paul C Langley
doaj +4 more sources
Epidemiological and pharmacoeconomic aspects of HIV infection in military
The goals of the research are to determine the latent morbidity and financial losses of the Russian Ministry of Defense due to the dismissal of service members with HIV infection at symptomatic stages; to establish the supposed clinical and ...
Yu. I. Bulankov +6 more
doaj +1 more source
Modelling the Health Economic Impact of Influenza Vaccination Strategies for High-Risk Children in Vietnam [PDF]
Introduction: In Vietnam, since 2011 a National Influenza Surveillance System in Vietnam has implemented Severe Acute Respiratory Infection (SARI) surveillance to assemble information and inform administrational and methods of prevention.
Trung Quang Vo +3 more
doaj +1 more source
Measuring health and health-related quality of life (HRQoL) is important for tracking the health of individuals and populations over time. Generic HRQoL measures allow for comparison across health conditions. One form of generic HRQoL measures are profile measures, which provide a description of health across several different domains (such as physical
Janel Hanmer +9 more
openaire +4 more sources
“The trouble with QALYs…” [PDF]
AbstractThis paper summarises the use of QALYs in evaluating changes in mental health states, highlighting the benefits and challenges of their use in this field. The general principles underlying the QALY measure and the most common methods of measuring QALYs are discussed briefly.
Knapp, M, Mangalore, R
openaire +2 more sources
The QALY is an impossible construct; it defies common sense. It fails completely once we consider the axioms of fundamental measurement. Utilities as ordinal scales cannot be used to create QALYS. The QALY should never have been introduced to support the
Paul Langley
doaj +1 more source
Current regulation of drug approvals has caused considerable controversy as entrusted to the National Institute of Clinical Excellence, and has led to a lack of availability of modern medicines on the basis of calculations made of 'value'.We have examined the assessment tool used by National Institute of Clinical Excellence (NICE) to establish the cost
R, Kirkdale +4 more
openaire +2 more sources
A new generation of aromatase inhibitors and target therapy directed at cycline-dependent kinases 4 and 6 gives a new opportunity to treat metastatic breast cancer. However, the cost of innovative therapy remains high.
S. L. Pavlinsky, P. I. Shabalkin
doaj +1 more source
Aim: To create the Russian-language version of the standardized international questionnaire Health Utilities Index (HUI) applicable for children's age, on the basis of the relevant international requirements to linguistic ratification and validation of ...
I. V. Vinyarskaya +4 more
doaj +1 more source

