Results 1 to 10 of about 74,894 (355)

A QALY is [still] a QALY is [still] a QALY? [PDF]

open access: goldBMC Medical Ethics
Despite clinical evidence of drug superiority, therapeutic modalities, like combination immunotherapy, are mostly considered cost-ineffective due to their high costs per life year(s) gained.
Hamideh Mahdiani   +2 more
doaj   +5 more sources

Abandoning Eugenics and the QALY

open access: yesINNOVATIONS in Pharmacy, 2021
Should decision making in health care, notably in respect of the allocation of resources between individuals and disease states, rest on notions of the burden of disease and denial of care as assessed by societal evaluations or on the extent to which the
Paul C Langley
doaj   +4 more sources

Epidemiological and pharmacoeconomic aspects of HIV infection in military

open access: yesЖурнал инфектологии, 2021
The goals of the research are to determine the latent morbidity and financial losses of the Russian Ministry of Defense due to the dismissal of service members with HIV infection at symptomatic stages; to establish the supposed clinical and ...
Yu. I. Bulankov   +6 more
doaj   +1 more source

Modelling the Health Economic Impact of Influenza Vaccination Strategies for High-Risk Children in Vietnam [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: In Vietnam, since 2011 a National Influenza Surveillance System in Vietnam has implemented Severe Acute Respiratory Infection (SARI) surveillance to assemble information and inform administrational and methods of prevention.
Trung Quang Vo   +3 more
doaj   +1 more source

The PROMIS of QALYs [PDF]

open access: yesHealth and Quality of Life Outcomes, 2015
Measuring health and health-related quality of life (HRQoL) is important for tracking the health of individuals and populations over time. Generic HRQoL measures allow for comparison across health conditions. One form of generic HRQoL measures are profile measures, which provide a description of health across several different domains (such as physical
Janel Hanmer   +9 more
openaire   +4 more sources

“The trouble with QALYs…” [PDF]

open access: yesEpidemiology and Psychiatric Sciences, 2007
AbstractThis paper summarises the use of QALYs in evaluating changes in mental health states, highlighting the benefits and challenges of their use in this field. The general principles underlying the QALY measure and the most common methods of measuring QALYs are discussed briefly.
Knapp, M, Mangalore, R
openaire   +2 more sources

The Great I-QALY Disaster

open access: yesINNOVATIONS in Pharmacy, 2020
The QALY is an impossible construct; it defies common sense. It fails completely once we consider the axioms of fundamental measurement. Utilities as ordinal scales cannot be used to create QALYS. The QALY should never have been introduced to support the
Paul Langley
doaj   +1 more source

The cost of a QALY [PDF]

open access: yesQJM, 2010
Current regulation of drug approvals has caused considerable controversy as entrusted to the National Institute of Clinical Excellence, and has led to a lack of availability of modern medicines on the basis of calculations made of 'value'.We have examined the assessment tool used by National Institute of Clinical Excellence (NICE) to establish the cost
R, Kirkdale   +4 more
openaire   +2 more sources

THE USE OF PALBOCKLIB, A CYCLINE-DEPENDENT KINASE 4/6 INHIBITOR, IN THE TREATMENT OF METASTATIC BREAST CANCER. A COST-CONSEQUENCE ANALYSIS

open access: yesСибирский онкологический журнал, 2017
A new generation of aromatase inhibitors and target therapy directed at cycline-dependent kinases 4 and 6 gives a new opportunity to treat metastatic breast cancer. However, the cost of innovative therapy remains high.
S. L. Pavlinsky, P. I. Shabalkin
doaj   +1 more source

VALIDATION OF THE RUSSIAN VERSION OF A QUESTIONNAIRE FOR THE ASSESSMENT OF UTILITARIAN INDICES IN PEDIATRIC PRACTICE. STAGE II

open access: yesВопросы современной педиатрии, 2014
Aim: To create the Russian-language version of the standardized international questionnaire Health Utilities Index (HUI) applicable for children's age, on the basis of the relevant international requirements to linguistic ratification and validation of ...
I. V. Vinyarskaya   +4 more
doaj   +1 more source

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