Results 11 to 20 of about 29,746 (162)

THE USE OF PALBOCKLIB, A CYCLINE-DEPENDENT KINASE 4/6 INHIBITOR, IN THE TREATMENT OF METASTATIC BREAST CANCER. A COST-CONSEQUENCE ANALYSIS

Сибирский онкологический журнал, 2017
A new generation of aromatase inhibitors and target therapy directed at cycline-dependent kinases 4 and 6 gives a new opportunity to treat metastatic breast cancer. However, the cost of innovative therapy remains high.
S. L. Pavlinsky, P. I. Shabalkin
doaj   +1 more source

VALIDATION OF THE RUSSIAN VERSION OF A QUESTIONNAIRE FOR THE ASSESSMENT OF UTILITARIAN INDICES IN PEDIATRIC PRACTICE. STAGE II

Вопросы современной педиатрии, 2014
Aim: To create the Russian-language version of the standardized international questionnaire Health Utilities Index (HUI) applicable for children's age, on the basis of the relevant international requirements to linguistic ratification and validation of ...
I. V. Vinyarskaya, V. V. Chernikov, R. N. Terletskaya, S. V. Shcherbakova, А. N. Fetisova   +4 more
doaj   +1 more source

Health economic evaluation of gene replacement therapies: methodological issues and recommendations

Journal of Market Access & Health Policy, 2020
Objective: To provide recommendations for addressing previously identified key challenges in health economic evaluations of Gene Replacement Therapies (GRTs), including: 1) the assessment of clinical effectiveness; 2) the valuation of health outcomes; 3)
Samuel Aballéa, Katia Thokagevistk, Rimma Velikanova, Steven Simoens, Lieven Annemans, Fernando Antonanzas, Pascal Auquier, Clément François, Frank-Ulrich Fricke, Daniel Malone, Aurélie Millier, Ulf Persson, Stavros Petrou, Omar Dabbous, Maarten Postma, Mondher Toumi   +15 more
doaj   +1 more source

DEVELOPMENT AND VALIDATION OF THE RUSSIAN VERSION OF THE QUESTIONNAIRE FOR THE UTILITARIAN INDEXES EVALUATION IN PEDIATRICIAN PRACTICE

Педиатрическая фармакология, 2012
Health-related quality of life (HRQL) is a value correlating with life duration, which depends on person’s disturbances, current functional condition, self-perception and social abilities, which are influenced by diseases, traumas, treatment and private ...
A. A. Baranov, V. J. Albitskiy, I. V. Vinyarskaya, V. V. Tchernikov, N. V. Ustinova, O. I. Simonova, J. V. Gorinova, M. S. Samsonova   +7 more
doaj   +1 more source

QALYs: The Basics

Value in Health, 2009
The aim of this article is to review the concept of the qualityadjusted life-year (QALY), a widely used measure of health improvement that is used to guide health-care resource allocation decisions. The QALY was originally developed as a measure of health effectiveness for cost-effectiveness analysis, a method intended to aid decision-makers charged ...
Weinstein, Milton C., Torrance, George, McGuire, Alistair   +2 more
openaire   +2 more sources

Cost-effectiveness study of the MitraClip system for mitral regurgitation treatment in inoperable patients

Евразийский Кардиологический Журнал, 2021
The study aims to estimate the MitraClip system’s cost-effectiveness compared with optimal medical therapy in adult patients with inoperable mitral regurgitation and assess its impact on the budget of the Russian Federation health system.Materials and ...
E. G. Fedina, K. A. Perova, T. S. Teptsova, D. S. Shchurov   +3 more
doaj   +1 more source

Pharmacoeconomic analysis of the use of tocilizumab in therapy for rheumatoid arthritis:imitation simulation

Научно-практическая ревматология, 2010
Heavy economic expenses for treatment with genetic engineering biologicals (GEB) in patients with rheumatoid arthritis (RA) determine what strategies are most optimal in terms of both their clinical efficiency and economic constituent should be sought ...
Dmitry Vladimirovich Goryachev, Sh F Erdes, E L Nasonov   +2 more
doaj   +1 more source

Pharmacoeconomic justification of the choice of specific therapy schemes for the treatment of adult patients with pulmonary arterial hypertension

Фармацевтичний журнал, 2022
Pulmonary arterial hypertension (PAH) is a progressive and debilitating disease that causes the blood vessels in the lungs to thicken and narrow, forcing the heart to pump blood through the lungs at high pressure. In recent years, a significant number
I. S. Datsenko, A. V. Kabachna
doaj   +1 more source

Availability and Pharmacoeconomics of Insulin Therapy in Countries with the Largest Number of Diabetics

Фармакоэкономика, 2019
The aim of the review was to analyze the availability of insulin therapy and the ways to improve it in countries with the largest number of patients with diabetes. It was also aimed to assess the medical, social and economic importance of insulin therapy
S. V. Ponomarenko
doaj   +1 more source

Economic evaluations of 13-valent pneumococcal conjugate vaccine: a systematic review

Expert Review of Vaccines, 2023
Introduction Studies on economic evaluations of the 13-valent pneumococcal conjugate vaccine (PCV13) have been increasing over the last decade. No systematic reviews have synthesized the evidence of economic evaluations of the PCV13.
Yuanze Du, Yi Wang, Ting Zhang, Juanjuan Li, Hewei Song, Yuanyuan Wang, Yifei Xu, Jingwen Cui, Ming Yang, Zengwu Wang, Xiuyun Wu, Chunping Wang   +11 more
doaj   +1 more source