Results 31 to 40 of about 22,680 (265)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Economic Evaluations of Artificial Intelligence Implementation in Diabetic Retinopathy Screening
Pharmacology and Clinical Pharmacy ResearchDiabetic retinopathy (DR) is a common complication of diabetes that damages retinal blood vessels and can lead to vision impairment. The application of Artificial Intelligence (AI) in DR screening offers a promising alternative to conventional methods ...
Ahmad Ahmad +2 more
doaj +1 more source
Фармакоэкономика, 2016 Study objective: pharmacoeconomic evaluation of cephalosporins, protected penicillins and macrolides, most commonly used in the treatment of acute obstructive bronchitis.Materials and methods.
O. V. Zhukova, S. V. Kononova
doaj +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Therapeutics and Clinical Risk Management, 2021 Yasinta Rakanita,1,2 Mas Rizky AA Syamsunarno,3 Rano K Sinuraya,1,4 Eka W Suradji,5,6 Rizky Abdulah,1,4 Auliya A Suwantika1,4,7 1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Bandung, Indonesia; 2College ...
Rakanita Y +5 more
doaj
Arthritis Care &Research, EarlyView.Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer +4 more
wiley +1 more source
Assessing the Economic Benefit of Mass COVID-19 Vaccination Program in Iran: A Real-World Modeling Study [PDF]
International Journal of Health Policy and ManagementBackground The global challenges posed by COVID-19 vaccinations require careful consideration by decision-makers at both the global and national levels, particularly in developing countries.
Hamidreza Jamaati +28 more
doaj +1 more source
Inhibitory role of inducible cAMP early repressor (ICER) in methamphetamine-induced locomotor sensitization. [PDF]
PLoS ONE, 2011 BACKGROUND: The inducible cyclic adenosine monophosphate (cAMP) early repressor (ICER) is highly expressed in the central nervous system and functions as a repressor of cAMP response element-binding protein (CREB) transcription.
Wenhua Han +7 more
doaj +1 more source
Karl Popper and the Mechanisms of Hydrogen Embrittlement
Advanced Engineering Materials, EarlyView.Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley +1 more source
Advanced Engineering Materials, EarlyView.A two‐dimensional multiscale finite element analysis framework was established for the first‐generation MoSiBTiC alloy, and the mechanical and fracture‐related parameters of the constituent phases were calibrated through experiments and simulations. The framework provides a basis for analyzing crack propagation behavior in its complex microstructure ...
Junfeng Du +4 more
wiley +1 more source