Results 31 to 40 of about 6,950 (262)

Briefing: The ICE’s Conservation Information Resource for Civil Engineers [PDF]

Proceedings of the Institution of Civil Engineers - Engineering History and Heritage, 2016
The Conservation Information Resource for Civil Engineers (Circe) is a new resource available on the Institution of Civil Engineers’ (ICE) website. It provides access to a wide range of information and guidance for civil and building engineers working on conservation, restoration and extension of the life of existing structures and is available to both
openaire   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Colonoscopy resource availability and colonoscopy utilization in Ontario, Canada

International Journal of Population Data Science, 2017
Objective Evidence of long wait times for colonoscopy and regional variations in colonoscopy utilization have raised concerns that the availability of colonoscopy resources may be insufficient to meet current needs.
Colleen Webber, Jennifer Flemming, Richard Birtwhistle, Mark Rosenberg, Patti Groome   +4 more
doaj   +1 more source

Adding salt to ice: Exploring students' cognitive resources

, 2019
University students in chemistry and physics were asked to predict, observe and explain what happens when some table salt is poured on an ice cube. Some base their initial responses on everyday events, such as their experience of salt being poured on icy roads, while others try to make predictions based on some scientific knowledge, such as freezing ...
Samuelsson, Christopher Robin, Haglund, Jesper, Elmgren, Maja   +2 more
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Reconstructed Russian Fisheries Catches in the Barents Sea: 1950-2014

Frontiers in Marine Science, 2018
The management of marine living resources that straddle country borders has historically been a challenge, particularly in cases where political tensions are high.
Sarah Popov, Dirk Zeller
doaj   +1 more source

Genomic analysis reveals neutral and adaptive patterns that challenge the current management regime for East Atlantic cod Gadus morhua L

Evolutionary Applications, 2020
Challenging long‐held perceptions of fish management units can help to protect vulnerable stocks. When a fishery consisting of multiple genetic stocks is managed as a single unit, overexploitation and depletion of minor genetic units can occur.
Torild Johansen, François Besnier, María Quintela, Per Erik Jorde, Kevin A. Glover, Jon‐Ivar Westgaard, Geir Dahle, Sigbjørn Lien, Matthew P. Kent   +8 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A Decade of Incorporating Social Sciences in the Integrated Marine Biosphere Research Project (IMBeR): Much Done, Much to Do?

Frontiers in Marine Science, 2021
Successful management and mitigation of marine challenges depends on cooperation and knowledge sharing which often occurs across culturally diverse geographic regions.
Ingrid van Putten, Ingrid van Putten, Rachel Kelly, Rachel D. Cavanagh, Eugene J. Murphy, Annette Breckwoldt, Stephanie Brodie, Christopher Cvitanovic, Christopher Cvitanovic, Mark Dickey-Collas, Mark Dickey-Collas, Lisa Maddison, Jess Melbourne-Thomas, Jess Melbourne-Thomas, Haritz Arrizabalaga, Kumiko Azetsu-Scott, Lynnath E. Beckley, Richard Bellerby, Richard Bellerby, Andrew J. Constable, Andrew J. Constable, Greg Cowie, Karen Evans, Marion Glaser, Julie Hall, Alistair J. Hobday, Alistair J. Hobday, Nadine M. Johnston, Joel K. Llopiz, Franz Mueter, Frank E. Muller-Karger, Kevin C. Weng, Dieter Wolf-Gladrow, José C. Xavier, José C. Xavier   +34 more
doaj   +1 more source