Results 91 to 100 of about 86,820 (316)
Aircraft icing research at NASA [PDF]
Research activity is described for: ice protection systems, icing instrumentation, experimental methods, analytical modeling for the above, and in flight research.
Olsen, W. A., Jr. +2 more
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
A passive infrared ice detection technique for helicopter applications [PDF]
A technique has been developed, and successfully tested, to detect icing remotely on helicopter rotor blades. Using passive infrared (IR) thermometry it is possible to detect the warming caused by latent heat released as supercooled water freezes. During
Dershowitz, Adam L. +1 more
core +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
An Experimental Study of Airfoil Icing Characteristics [PDF]
A full scale general aviation wing with a NACA 63 sub 2 A415 airfoil section was tested to determine icing characteristics for representative rime and glaze icing conditions.
Shaw, R. J., Solano, F. R., Sotos, R. G.
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
A Review of Wind Turbine Icing and Anti/De-Icing Technologies
EnergiesThe development and utilization of clean energy is becoming more extensive, and wind power generation is one of the key points of this. Occasionally, wind turbines are faced with various extreme environmental impacts such as icing, lightning strikes and ...
Zhijin Zhang +4 more
doaj +1 more source
Preliminary Survey of Icing Conditions Measured During Routine Transcontinental Airline Operation [PDF]
Icing data collected on routine operations by four DC-4-type aircraft equipped with NACA pressure-type icing-rate meters are presented as preliminary information obtained from a statistical icing data program sponsored by the NACA with the cooperation of
Perkins, Porter J.
core +1 more source
Voices in Bioethics, 2014 While abhorrent by any standard, the Nazi medical experimentation has become a core illustration of unethically collected data currently being used in scientific research.1-4 Due to the extremes achieved – near-to sub-zero temperatures in investigating hypothermia and its effect on the body – some medical and scientific researchers have claimed it ...
openaire +2 more sources