Results 111 to 120 of about 86,820 (316)

The Surface Expression of Ice Segregation: Needle Ice, Pebble Ice, Ice Flowers and Hair Ice

open access: yesJournal of Geography and Earth Sciences, 2021
James R. Carter, Emeritus Professor
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Structural properties of impact ices accreted on aircraft structures [PDF]

open access: yes
The structural properties of ice accretions formed on aircraft surfaces are studied. The overall objectives are to measure basic structural properties of impact ices and to develop finite element analytical procedures for use in the design of all deicing
Chu, M. L., Scavuzzo, R. J.
core   +1 more source

Effect of weather conditions on airport operations [PDF]

open access: yes, 1979
The effect of adverse weather on airport operations are discussed.
Ginty, D. F.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Icing simulation: A survey of computer models and experimental facilities [PDF]

open access: yes
A survey of the current methods for simulation of the response of an aircraft or aircraft subsystem to an icing encounter is presented. The topics discussed include a computer code modeling of aircraft icing and performance degradation, an evaluation of ...
Potapczuk, M. G., Reinmann, J. J.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Flexible and scalable photothermal/electro thermal anti-icing/de-icing metamaterials for effective large-scale preparation

open access: yesiScience
Summary: Anti-icing and de-icing are vital for infrastructure maintenance. While carbon-based materials with photothermal or electrothermal effects have advanced, they face challenges like environmental dependence, poor resistance, high energy ...
Tonghui Lu   +8 more
doaj   +1 more source

NACA Investigations of Icing-Protection Systems for Turbojet-Engine Installations [PDF]

open access: yes
Investigations have been made in flight and in wind tunnels to determine which components of turbojet installations are most critical in icing conditions, and to evaluate several methods of icing protection. From these studies, the requirements necessary
Callaghan, Edmund E.   +2 more
core   +1 more source

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