Results 121 to 130 of about 86,820 (316)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Icing Characteristics and Anti-Icing Heat Requirements for Hollow and Ternally Modified Gas-Heated Inlet Guide Vanes [PDF]
A two-dimensional inlet-guide-vane cascade was investigated to determine the effects of ice formations on the pressure losses across the guide vanes and to evaluate the heated gas flow and temperature required to prevent Icing at various conditions.
Bowden, Dean T., Gray, Vernon H.
core +1 more source
Auditor’s Liability and the Need for Increased Accounting Uniformity [PDF]
, 1965 The work aims to study different methods suitable for de-icing and ice prevention of vehicle headlamps and tail lamps, especially LED-lights. Furthermore, the work aims to investigate the scale of the problem with insufficient or lack of de-icing on ...
Bradley, Edwin J.
core +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Investigation of Icing Characteristics of Typical Light Airplane Engine Induction Systems [PDF]
The icing characteristics of two typical light-airplane engine induction systems were investigated using the carburetors and manifolds of engines in the horsepower ranges from 65 to 85 and 165 to 185.
Coles, W. D.
core +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Zhongguo dianliUnder the meteorological factors of icing, the changes of icing thickness, shape and distribution on transmission conductor with time cumulation affect the safety operation of power grid system.
Chuanqi WANG +4 more
doaj +1 more source
Study of ice accretion on icing wind tunnel components [PDF]
In a closed loop icing wind tunnel the icing cloud is simulated by introducing tiny water droplets through an array of nozzles upstream of the test section.
Newton, J. E., Olsen, W.
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source