Results 51 to 60 of about 26,227 (281)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

NRC Marine Icing Database [PDF]

open access: yes, 2005
Vessels operating in northern waters during the winter months constantly face a hazard of icing. This applies particularly to the Canadian east coast fishing vessels.
Kubat, Ivana, Timco, Garry
core   +1 more source

On the Fidelity of RANS-Based Turbulence Models in Modeling the Laminar Separation Bubble and Ice-Induced Separation Bubble at Low Reynolds Numbers on Unmanned Aerial Vehicle Airfoil

open access: yesDrones
The operational regime of Unmanned Aerial Vehicles (UAVs) is distinguished by the dominance of laminar flow and the flow field is characterized by the appearance of Laminar Separation Bubbles (LSBs). Ice accretion on the leading side of the airfoil leads
Manaf Muhammed, Muhammad Shakeel Virk
doaj   +1 more source

Performance Analysis of Electro-Impulse De-icing Device for Overhead Ground Wire

open access: yesAdvances in Electrical and Computer Engineering, 2022
The icing disaster of the overhead ground wire seriously affects the safe and stable operation of the power grid system. Compared with the traditional thermal ice melting technology, the mechanical de-icing technology has obvious advantages such as ...
ZHOU, X., ZHU, Y., SUN, S., CAI, X.
doaj   +1 more source

Breaking the ice with ICE

open access: yes, 2020
Aortic insufficiency with recirculation syndrome can be a difficult diagnosis to make in patients with continuous flow left ventricular assist devices as it is generally underestimated by traditional transthoracic echocardiography. Transesophageal echocardiography can also underestimate aortic insufficiency and requires general anesthesia, which can be
Charlene Rohm   +5 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Computer-Assisted Aircraft Anti-Icing Fluids Endurance Time Determination

open access: yesAerospace, 2020
Deicing and anti-icing the aircraft using proper chemical fluids, prior takeoff, are mandatory. A thin layer of ice or snow can compromise the safety, causing lift loss and drag increase.
David Gagnon   +3 more
doaj   +1 more source

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