Small, Volume 22, Issue 32, 8 June 2026.Coarse‐grained simulations show that the formation of transient anionic–cationic lipid pairs regulates the rate‐limiting step for the lamellar‐to‐hexagonal phase transition in mixtures of anionic and cationic lipids mimicking the endosomal membrane after fusion with lipid‐based nanoparticles, thus playing an important role in the endosomal escape of ...
David Noel Zimmer +2 more
wiley +1 more source
Bayesian Optimization of Catalysis with In-Context Learning. [PDF]
ACS Cent SciCaldas Ramos M +3 more
europepmc +1 more source
A novel fusion tool to enable G protein‐coupled receptor structure determination
Acta Crystallographica Section D, Volume 82, Issue 6, Page 655-663, June 2026.The development of a new fusion tool in which a β‐lactamase fusion tag and a binding partner enabled the structure determination of an antagonist‐bound G protein‐coupled receptor by cryo‐EM is reported.Structure determination of G protein‐coupled receptors (GPCRs) plays an important role in accelerating drug development against this medically important
Nita R. Shah +14 more
wiley +1 more source
Residual refraction after myopic implantable collamer lens implantation: clinical data vs optical models. [PDF]
Int OphthalmolOleszko A +2 more
europepmc +1 more source
GGAs: Regulation of Multiple Sorting Pathways and Potential Association With Human Diseases
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Golgi‐localized gamma‐ear‐containing Arf‐binding proteins (GGAs) are a family of monomeric clathrin adaptors that function in intracellular vesicle trafficking. The three GGA family members—GGA1, GGA2 and GGA3—were first identified as sorting adaptors almost simultaneously by independent research groups in 2000. It is now well established that
Qinqin Wang +5 more
wiley +1 more source
Resource profiles and suicide attempts in youth with disabilities
Journal of Child Psychology and Psychiatry, Volume 67, Issue 6, Page 976-987, June 2026.Background The issue of suicide among youth with disabilities transitioning into adulthood is a serious public health issue. In navigating this transition, youth with disabilities encounter unique obstacles that require careful consideration and support.
Minhae Cho +4 more
wiley +1 more source
Dynamic Lysine Acetylation Disrupts Isocitrate Lyase Function and Enables Metabolic Optimisation. [PDF]
Microb BiotechnolMartínez-Vivancos A +6 more
europepmc +1 more source
Learning and distraction: Evidence for cognitive load interference in medical education
Medical Education, Volume 60, Issue 6, Page 676-684, June 2026.Abstract Background Distraction may increase cognitive load. Cues may decrease it. But what happens if we cue in distracted learning environments? Does effective instruction buffer against the detrimental effects of distraction? Methods In a 2 × 2 factorial experiment, 117 s–year medical students without prior knowledge watched a standardised ...
Andrea Storck +8 more
wiley +1 more source
Comparison of refractive outcomes and visual quality between femtosecond laser-assisted arcuate keratotomy and steep-axis meridian clear corneal incision combined with Implantable Collamer Lens (ICL) implantation for the correction of moderate-to-high myopia and low astigmatism. [PDF]
BMC OphthalmolMao Z +8 more
europepmc +1 more source
The Effector SIX8 Contributes to Virulence of Fusarium oxysporum f. sp. lactucae Race 4 on Lettuce
Molecular Plant Pathology, Volume 27, Issue 6, June 2026.Secreted in Xylem (SIX) genes were expressed during infection of lettuce by Fusarium oxysporum f. sp. lactucae race 4 (Fola4). CRISPR‐Cas9 knockout of the SIX8 gene in Fola4 reduced virulence in lettuce which was restored following Agrobacterium mediated complementation. SIX8 therefore contributes to virulence of Fola4 on lettuce.
Andrew D. Legg +4 more
wiley +1 more source