Results 221 to 230 of about 65,932 (320)

In Situ Synthesis of Covalent Organic Frameworks Inside Cells for Triggering Ferroptosis and Immunotherapy

Advanced Materials, Volume 38, Issue 16, 17 March 2026.
We have developed an intracellular crystalline polymerization strategy involving acid‐catalyzed imine condensation to synthesize COFs in lysosomes. The generation of COFs in lysosomes damages their integrity, activates iron species, and induces immunogenic ferroptosis, thereby enhancing antitumor immunotherapy.
Qun Guan, Le‐Le Zhou, Zhiqing Yang, Yan‐An Li, Leyong Wang, Ruibing Wang   +5 more
wiley   +1 more source

Molecular insights into the role of desmin intermediate filament network in chromatin landscape, cardiomyocyte differentiation, and maturation. [PDF]

Cell Death Dis
Tsikitis M, Diokmetzidou A, Liakopoulos P, Karipidou M, Kokkinopoulos I, Vatsellas G, Kloukina I, Kolovos P, Capetanaki Y.   +8 more
europepmc   +1 more source

Reveal LINQ ICM

, 2021
openaire   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, Volume 13, Issue 14, 9 March 2026.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

PROTAC-PatentDB: A PROTAC Patent Compound Dataset. [PDF]

Sci Data
Cai H, Yao G, Shi Y, Zhang T, Hu Y.
europepmc   +1 more source

Iohexol as an Emerging Contaminant Potentially Influencing Structural and Functional Changes in the Activated Sludge Microbiome. [PDF]

Molecules
Nowak A, Pacwa-Płociniczak M, Guzik U, Wojcieszyńska D.   +3 more
europepmc   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang, Shucheng Jin, Penghui Guo, Yuying Yin, Yichun Hua, Xiaosheng Ding, Zhe Zhang, Shuo Chen, Xu Han, Baowang Li, Yan Liu, Xiaoyan Li, Deling Li, Jing Jing, Wei Shi, Wang Jia   +15 more
wiley   +1 more source

<i>Mycobacterium tuberculosis</i> Modulates the Expansion of Terminally Exhausted CD4⁺ and CD8⁺ T-Cells in Individuals with HIV-TB Co-Infection. [PDF]

Pathogens
Sharma K, Sharma A, Arora SK.
europepmc   +1 more source

Genetic architecture of plasma pTau217 and related biomarkers in Alzheimer's disease via genome‐wide association studies

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION We aimed to define the genetic architecture and regulatory mechanisms of Alzheimer's disease (AD) ‐related plasma biomarkers in an East Asian population. METHODS Genome‐wide association studies (GWAS) of plasma phosphorylated tau at threonine 217 (pTau217), pTau181, neurofilament light chain (NfL), and glial fibrillary acidic ...
Jun Pyo Kim, Minku Song, Minyoung Cho, Hyunwoo Lee, Sang‐Hyuk Jung, Soohyun Lim, Chanhee Kim, Beomjin Jang, Daeun Shin, Heekyoung Kang, Sohyun Yim, Hyemin Jang, Bo‐Hyun Kim, Hee Jin Kim, Duk L. Na, Joon‐Yong An, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez‐Ortiz, Nicholas J. Ashton, Theresa A. Day, Sang Won Seo, Hong‐Hee Won   +22 more
wiley   +1 more source

Metabolic Culture Medium Enhances Maturation of Human iPSC-Derived Cardiomyocytes via Cardiac Troponin I Isoform Induction. [PDF]

Int J Mol Sci
Goliusova DV, Bogomolova AP, Davidenko AV, Lavrenteva KA, Sharikova MY, Zerkalenkova EA, Vassina EM, Bogomazova AN, Lagarkova MA, Katrukha IA, Lebedeva OS.   +10 more
europepmc   +1 more source