Neural mechanisms of the temporal response of cortical neurons to intracortical microstimulation [PDF]
Brain Stimulation, 2023 Background: Intracortical microstimulation (ICMS) is used to map neuronal circuitry in the brain and restore lost sensory function, including vision, hearing, and somatosensation.
Warren M Grill, Karthik Kumaravelu
exaly +7 more sources
Low-threshold, high-resolution, chronically stable intracortical microstimulation by ultraflexible electrodes [PDF]
Cell Reports, 2023 Summary: Intracortical microstimulation (ICMS) enables applications ranging from neuroprosthetics to causal circuit manipulations. However, the resolution, efficacy, and chronic stability of neuromodulation are often compromised by adverse tissue ...
Lan Luan, Chong Xie
exaly +6 more sources
Stoney vs. Histed: Quantifying the spatial effects of intracortical microstimulation [PDF]
Brain Stimulation, 2022 Background: Intracortical microstimulation (ICMS) is used to map neural circuits and restore lost sensory modalities such as vision, hearing, and somatosensation.
Joseph Sombeck +2 more
exaly +8 more sources
Responses of Cortical Neurons to Intracortical Microstimulation in Awake Primates. [PDF]
eNeuro, 2023 Intracortical microstimulation (ICMS) is commonly used in many experimental and clinical paradigms; however, its effects on the activation of neurons are still not completely understood.
Yun R +4 more
europepmc +4 more sources
Intracortical microstimulation induces rapid microglia process convergence. [PDF]
BiomaterialsIntracortical microstimulation (ICMS) has demonstrated the potential to restore vision and hearing by stimulating relevant cortical regions in both animals and humans, offering significant clinical promise for sensory restoration.
Williams NP +4 more
europepmc +4 more sources
Amplitude- and frequency-dependent activation of layer II/III neurons by intracortical microstimulation [PDF]
iScience, 2023 Summary: Intracortical microstimulation (ICMS) has been used for the development of brain machine interfaces. However, further understanding about the spatiotemporal responses of neurons to different electrical stimulation parameters is necessary to ...
Guangying K. Wu +5 more
doaj +3 more sources
Reducing Behavioral Detection Thresholds per Electrode via Synchronous, Spatially-Dependent Intracortical Microstimulation [PDF]
Frontiers in Neuroscience, 2022 Intracortical microstimulation (ICMS) has shown promise in restoring quality of life to patients suffering from paralysis, specifically when used in the primary somatosensory cortex (S1).
Nicolas G. Kunigk +9 more
doaj +3 more sources
The Role of Electrode-Site Placement in the Long-Term Stability of Intracortical Microstimulation [PDF]
Frontiers in Neuroscience, 2021 Intracortical microelectrodes are neuroprosthetic devices used in brain-machine interfaces to both record and stimulate neural activity in the brain. These technologies have been improved by advances in microfabrication, which have led to the creation of
Kevin J Otto, Morgan Urdaneta
exaly +4 more sources
Intracortical microstimulation of human somatosensory cortex induces natural perceptual biases [PDF]
Brain StimulationTime-order error, a psychophysical phenomenon in which the duration in between successive stimuli alters perception, has been studied for decades by neuroscientists and psychologists. To date, however, the locus of these effects is unknown.
Charles M. Greenspon +4 more
doaj +3 more sources
Subthreshold intracortical microstimulation of human somatosensory cortex enhances tactile sensitivity [PDF]
Brain StimulationBackground: Intracortical microstimulation (ICMS) of the somatosensory cortex activates neurons around the stimulating electrodes and can elicit tactile sensations. Objective: It is not clear how the direct activation of cortical neurons influences their
Luke E. Osborn +15 more
doaj +3 more sources