Results 21 to 30 of about 3,887 (186)
A Machine Learning-Based Decoder Framework for the Cortical Voltage-Sensitive Dye Responses to Retinal Neuromorphic Microstimulation: A Proof-of-Concept Simulation Study [PDF]
BioengineeringIntracortical microstimulation (ICMS) is a promising approach for visual prostheses. We recently proposed using retinal neuromorphic spike trains derived from visual images as ICMS pulse sequences, and preliminarily recorded cortical voltage-sensitive ...
Keisuke Yamada +3 more
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Layer-specific parameters of intracortical microstimulation of the somatosensory cortex. [PDF]
J Neural Eng, 2021 Abstract Objective . Intracortical microstimulation of the primary somatosensory cortex (S1) has shown great progress in restoring touch sensations to patients with paralysis. Stimulation parameters such as amplitude, phase duration, and frequency can influence the quality of the evoked percept
Urdaneta ME +4 more
europepmc +4 more sources
Optimal interphase delay in biphasic current pulses facilitates neural circuit activation induced by microstimulation in the mouse visual cortex [PDF]
Frontiers in NeuroscienceCathodic-first biphasic current pulses are commonly employed in intracortical microstimulation. Due to the intricate arrangement of axons, somata, and dendrites in the cerebral cortex, membrane polarizations induced by the cathodic and subsequent anodic ...
Santa Fukuda, Yuki Hayashida
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Neural mechanisms underlying intracortical microstimulation for sensory restoration. [PDF]
Nat Biomed EngSensation plays a pivotal role in the orchestration of our daily lives. Intracortical microstimulation (ICMS) can elicit artificial sensations in persons who have lost sensation due to neurological injury or disease. Despite ongoing clinical studies to assess the safety and efficacy of ICMS, the mechanisms underlying neural activation by ICMS and their
Hughes C, Chen X, Grill W, Kozai TDY.
europepmc +3 more sources
Intracortical Microstimulation Modulates Cortical Induced Responses. [PDF]
J Neurosci, 2018 Recent advances in cortical prosthetics relied on intracortical microstimulation (ICMS) to activate the cortical neural network and convey information to the brain. Here we show that activity elicited by low-current ICMS modulates induced cortical responses to a sensory stimulus in the primary auditory cortex (A1).
Voigt MB, Yusuf PA, Kral A.
europepmc +4 more sources
Brain Stimulation, 2021 Background: Previous studies have shown that neurons of the cerebral cortex can be injured by implantation of, and stimulation with, implanted microelectrodes.
Douglas McCreery +3 more
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Equalization for intracortical microstimulation artifact reduction [PDF]
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2013 We present a method for decreasing the duration of artifacts present during intra-cortical microstimulation (ICMS) recordings by using techniques developed for digital communications. We replace the traditional monophasic or biphasic current stimulation pulse with a patterned pulse stream produced by a Zero Forcing Equalizer (ZFE) filter after ...
Philip Chu +5 more
openaire +4 more sources
A computational model that predicts behavioral sensitivity to intracortical microstimulation. [PDF]
J Neural Eng, 2017 Intracortical microstimulation (ICMS) is a powerful tool to investigate the neural mechanisms of perception and can be used to restore sensation for patients who have lost it. While sensitivity to ICMS has previously been characterized, no systematic framework has been developed to summarize the detectability of individual ICMS pulse trains or the ...
Kim S, Callier T, Bensmaia SJ.
europepmc +3 more sources
Multimodal, longitudinal assessment of intracortical microstimulation. [PDF]
Prog Brain Res, 2011 The fundamental obstacle to neuroprostheses based on penetrating microstimulation is the tissue's response to the device insertion and to the application of the electrical stimulation. Our long-term goal is to develop multichannel microstimulation of central nervous tissue for clinical therapy.
Koivuniemi A +3 more
europepmc +4 more sources
High density nanowire electrodes for intracortical microstimulation [PDF]
2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019 High-density electrodes with the nano feature size greatly enhance resolution and specificity during intracortical microstimulation. In this viewpoint, we fabricated and developed high-density nanowire (NW) electrodes, ~ 2.45×109 / cm2 that could directly stimulate specific region of the cortex with low current amplitude in the range of 120-180 μA. The
Srinivasu Valagerahally Puttaswamy +5 more
openaire +2 more sources