Results 31 to 40 of about 15,463 (165)

Electrochemical characterization and chronic stability of Utah electrode arrays for intracortical microstimulation [PDF]

Frontiers in Neuroscience
This study presents methods for evaluating the long-term electrochemical stability of Utah electrode arrays (UEAs) encapsulated with amorphous silicon carbide (a-SiC) or Parylene-C for intracortical microstimulation (ICMS).
Christopher K. Nguyen, Brandon S. Sturgill, Balaji Srikanthan, Behnoush Dousti, Madhav Bhatt, Mahasty Khajehzadeh, Soham Mangarolia, Nashita Hasan, Ana G. Hernandez-Reynoso, Sandeep Negi, Stuart F. Cogan   +10 more
doaj   +2 more sources

The unexpected sight: improvement of visual function following intracortical microstimulation of the human occipital cortex. [PDF]

Brain Commun
We describe the case of a participant in a clinical trial investigating intracortical microstimulation of the visual cortex to provide a limited yet functional sense of vision to the profoundly blind.
Alfaro A, Soo L, Waclawczyk D, Morollón R, Grani F, Fernandez E.   +5 more
europepmc   +2 more sources

High density nanowire electrodes for intracortical microstimulation [PDF]

Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual International Conference, 2019
High-density electrodes with the nano feature size greatly enhance resolution and specificity during intracortical microstimulation. In this viewpoint, we fabricated and developed high-density nanowire (NW) electrodes, ~ 2.45×109 / cm2 that could directly stimulate specific region of the cortex with low current amplitude in the range of 120-180 μA. The
James McLaughlin, Qiongfeng Shi, Chengkuo Lee   +2 more
exaly   +3 more sources

Long-term safety and efficacy of intracortical microstimulation in humans. [PDF]

Sci Transl Med
Intracortical microstimulation (ICMS) of somatosensory cortex can restore a sense of touch to people with spinal cord injury. In this early feasibility clinical trial (NCT01894802), we evaluated the safety, efficacy, and longevity of ICMS because there ...
Greenspon CM, Hobbs TG, Verbaarschot C, Alamri AH, Shelchkova ND, Lienkämper R, Ye J, Simpson TW, Weiss JM, Weir DM, Harrington DE, Van Driesche A, Satzer D, Valle G, Miller LE, Hatsopoulos NG, Gonzalez-Martinez J, Warnke PC, Downey JE, Boninger ML, Collinger JL, Gaunt RA.   +21 more
europepmc   +2 more sources

A computational model that predicts behavioral sensitivity to intracortical microstimulation. [PDF]

J Neural Eng, 2017
Intracortical microstimulation (ICMS) is a powerful tool to investigate the neural mechanisms of perception and can be used to restore sensation for patients who have lost it. While sensitivity to ICMS has previously been characterized, no systematic framework has been developed to summarize the detectability of individual ICMS pulse trains or the ...
Kim S, Callier T, Bensmaia SJ.
europepmc   +3 more sources

Intracortical Microstimulation Parameters Dictate the Amplitude and Latency of Evoked Responses

Brain Stimulation, 2016
Microstimulation of brain tissue plays a key role in a variety of sensory prosthetics, clinical therapies and research applications. However, the effects of stimulation parameters on the responses they evoke remain widely unknown.We aimed to investigate the contribution of each stimulation parameter to the response and identify interactions existing ...
Numa Dancause, Mohamad Sawan, Meghan Watson   +2 more
exaly   +3 more sources

The effect of chronic intracortical microstimulation on the electrode-tissue interface. [PDF]

J Neural Eng, 2014
Somatosensation is critical for effective object manipulation, but current upper limb prostheses do not provide such feedback to the user. For individuals who require use of prosthetic limbs, this lack of feedback transforms a mundane task into one that requires extreme concentration and effort.
Chen KH, Dammann JF, Boback JL, Tenore FV, Otto KJ, Gaunt RA, Bensmaia SJ.   +6 more
europepmc   +4 more sources

Complex forelimb movements and cortical topography evoked by intracortical microstimulation in male and female mice. [PDF]

Cereb Cortex, 2023
Brown AR, Mitra S, Teskey GC, Boychuk JA.   +3 more
europepmc   +2 more sources

Behavioral assessment of sensitivity to intracortical microstimulation of primate somatosensory cortex. [PDF]

Proc Natl Acad Sci U S A, 2015
Significance Electrical stimulation of sensory structures in the brain is a powerful tool to investigate neural circuits and may provide a means to restore sensation for patients for whom stimulation of the nerve is not an option. For both purposes, however, it is critical to understand how the design of the stimulation shapes the ...
Kim S, Callier T, Tabot GA, Gaunt RA, Tenore FV, Bensmaia SJ.   +5 more
europepmc   +4 more sources

Astrocytes modulate stimulation-induced neural activity during intracortical microstimulation

Brain Stimulation
Kevin Stieger, Alberto Vazquez, Takashi Kozai   +2 more
doaj   +2 more sources