Intracortical Microstimulation Parameters Dictate the Amplitude and Latency of Evoked Responses
Microstimulation of brain tissue plays a key role in a variety of sensory prosthetics, clinical therapies and research applications. However, the effects of stimulation parameters on the responses they evoke remain widely unknown.We aimed to investigate the contribution of each stimulation parameter to the response and identify interactions existing ...
Numa Dancause, Mohamad Sawan
exaly +3 more sources
FMRI activity in the macaque cerebellum evoked by intracortical microstimulation of the primary somatosensory cortex: evidence for polysynaptic propagation. [PDF]
Simultaneous electrical microstimulation (EM) and functional magnetic resonance imaging (fMRI) is a useful tool for probing connectivity across brain areas in vivo.
Teppei Matsui +8 more
doaj +3 more sources
Behavioral assessment of sensitivity to intracortical microstimulation of primate somatosensory cortex. [PDF]
Significance Electrical stimulation of sensory structures in the brain is a powerful tool to investigate neural circuits and may provide a means to restore sensation for patients for whom stimulation of the nerve is not an option. For both purposes, however, it is critical to understand how the design of the stimulation shapes the evoked ...
Kim S +5 more
europepmc +4 more sources
Optical imaging of cortical networks via intracortical microstimulation.
Understanding cortical organization is key to understanding brain function. Distinct neural networks underlie the functional organization of the cerebral cortex; however, little is known about how different nodes in the cortical network interact during perceptual processing and motor behavior. To study cortical network function we examined whether the
Brock AA, Friedman RM, Fan RH, Roe AW.
europepmc +4 more sources
Tactile feedback is essential for grip force control when operating a neuroprosthesis. Due to limited knowledge of cortical sensorimotor coordination, artificial feedback is mostly counterintuitive, requiring training to be associated with grasping ...
Qi Zhang +9 more
doaj +2 more sources
Complex forelimb movements and cortical topography evoked by intracortical microstimulation in male and female mice. [PDF]
Brown AR +3 more
europepmc +2 more sources
A Machine Learning-Based Decoder Framework for the Cortical Voltage-Sensitive Dye Responses to Retinal Neuromorphic Microstimulation: A Proof-of-Concept Simulation Study [PDF]
Intracortical microstimulation (ICMS) is a promising approach for visual prostheses. We recently proposed using retinal neuromorphic spike trains derived from visual images as ICMS pulse sequences, and preliminarily recorded cortical voltage-sensitive ...
Keisuke Yamada +3 more
europepmc +2 more sources
Optimal interphase delay in biphasic current pulses facilitates neural circuit activation induced by microstimulation in the mouse visual cortex. [PDF]
Cathodic-first biphasic current pulses are commonly employed in intracortical microstimulation. Due to the intricate arrangement of axons, somata, and dendrites in the cerebral cortex, membrane polarizations induced by the cathodic and subsequent anodic ...
Fukuda S, Hayashida Y.
europepmc +2 more sources
Ultra-Miniaturised CMOS Current Driver for Wireless Biphasic Intracortical Microstimulation [PDF]
This work shows an ultra-miniaturised and ultra-low-power CMOS current driver for biphasic intracortical microstimulation. The CMOS driver is composed of a leakage-based voltage-to-current converter and an H-bridge circuit providing biphasic charge ...
Barbruni, Gian Luca +4 more
core +4 more sources
Background: Previous studies have shown that neurons of the cerebral cortex can be injured by implantation of, and stimulation with, implanted microelectrodes.
Douglas McCreery +3 more
doaj +1 more source

