Results 11 to 20 of about 1,691 (139)

Responses of Cortical Neurons to Intracortical Microstimulation in Awake Primates. [PDF]

open access: yeseNeuro, 2023
Abstract Intracortical microstimulation (ICMS) is commonly used in many experimental and clinical paradigms; however, its effects on the activation of neurons are still not completely understood. To document the responses of cortical neurons in awake nonhuman primates to stimulation, we recorded single-unit activity while delivering ...
Yun R   +4 more
europepmc   +3 more sources

Amplitude- and frequency-dependent activation of layer II/III neurons by intracortical microstimulation [PDF]

open access: yesiScience, 2023
Summary: Intracortical microstimulation (ICMS) has been used for the development of brain machine interfaces. However, further understanding about the spatiotemporal responses of neurons to different electrical stimulation parameters is necessary to ...
Guangying K. Wu   +5 more
doaj   +2 more sources

Neural Modulation of the Primary Auditory Cortex by Intracortical Microstimulation with a Bio-Inspired Electronic System [PDF]

open access: yesBioengineering, 2020
Nowadays, the majority of the progress in the development of implantable neuroprostheses has been achieved by improving the knowledge of brain functions so as to restore sensorial impairments.
Maria Giovanna Bianco   +6 more
doaj   +2 more sources

Layer-specific parameters of intracortical microstimulation of the somatosensory cortex. [PDF]

open access: yesJ Neural Eng, 2021
Abstract Objective . Intracortical microstimulation of the primary somatosensory cortex (S1) has shown great progress in restoring touch sensations to patients with paralysis. Stimulation parameters such as amplitude, phase duration, and frequency can influence the quality of the evoked percept
Urdaneta ME   +4 more
europepmc   +4 more sources

Intracortical microstimulation induces rapid microglia process convergence. [PDF]

open access: yesBiomaterials
Abstract Intracortical microstimulation (ICMS) has demonstrated the potential to restore vision and hearing by stimulating relevant cortical regions in both animals and humans, offering significant clinical promise for sensory restoration.
Williams NP   +4 more
europepmc   +3 more sources

Subthreshold intracortical microstimulation of human somatosensory cortex enhances tactile sensitivity [PDF]

open access: yesBrain Stimulation
Background: Intracortical microstimulation (ICMS) of the somatosensory cortex activates neurons around the stimulating electrodes and can elicit tactile sensations. Objective: It is not clear how the direct activation of cortical neurons influences their
Luke E. Osborn   +15 more
doaj   +2 more sources

Neural mechanisms underlying intracortical microstimulation for sensory restoration. [PDF]

open access: yesNat Biomed Eng
Sensation plays a pivotal role in the orchestration of our daily lives. Intracortical microstimulation (ICMS) can elicit artificial sensations in persons who have lost sensation due to neurological injury or disease. Despite ongoing clinical studies to assess the safety and efficacy of ICMS, the mechanisms underlying neural activation by ICMS and their
Hughes C, Chen X, Grill W, Kozai TDY.
europepmc   +3 more sources

Intracortical Microstimulation Modulates Cortical Induced Responses. [PDF]

open access: yesJ Neurosci, 2018
Recent advances in cortical prosthetics relied on intracortical microstimulation (ICMS) to activate the cortical neural network and convey information to the brain. Here we show that activity elicited by low-current ICMS modulates induced cortical responses to a sensory stimulus in the primary auditory cortex (A1).
Voigt MB, Yusuf PA, Kral A.
europepmc   +4 more sources

Electrochemical characterization and chronic stability of Utah electrode arrays for intracortical microstimulation [PDF]

open access: yesFrontiers in Neuroscience
This study presents methods for evaluating the long-term electrochemical stability of Utah electrode arrays (UEAs) encapsulated with amorphous silicon carbide (a-SiC) or Parylene-C for intracortical microstimulation (ICMS).
Christopher K. Nguyen   +10 more
doaj   +2 more sources

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