Results 231 to 240 of about 65,932 (320)

AI‐Based Prediction of PROTAC‐ and Molecular Glue‐Mediated Ternary Complexes: A Comparative Evaluation of AlphaFold 3 and Boltz‐2

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
Superposition of the lowest RMSD predictions for the ternary complex of SMARCA2‐VHL. The AlphaFold 3 prediction is shown in cyan, the Boltz‐2 prediction in pink, and the reference X‐ray structure in green. ABSTRACT Proteolysis targeting chimeras (PROTACs) and molecular glues induce ligand‐mediated ternary complexes between an E3 ubiquitin ligase and a ...
Lino Riepenhausen, Anne‐Christin Sarnow, Dina Robaa, Wolfgang Sippl   +3 more
wiley   +1 more source

Characterizing Evoked Movement Patterns and Connectivity in Sensorimotor Cortex After Sensory Loss in Squirrel Monkeys. [PDF]

J Comp Neurol
Qi HX, Liao CC, Reed JL, Stepniewska I, Wang Q, Kaas JH.   +5 more
europepmc   +1 more source

ALKBH3 suppresses ischemia/reperfusion‐induced PANoptosis by regulating the ZBED6/STAT1/AIM2 axis through m1A demethylation

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
ALKBH3 alleviates myocardial ischemia/reperfusion injury by suppressing PANoptosis. ALKBH3 promotes ZBED6 translation via mRNA m1A demethylation. ZBED6 promotes the interaction between STAT1 and NEDD4L to facilitate STAT1 ubiquitination and subsequent degradation.
Hongtao Diao, Chunlei Wang, Yuting Xiong, Qiaoyue Zhao, Xinyue Zhang, Xiaohui Qi, Yuan Zou, Jiaxuan Li, Linghua Zeng, Wei Si, Feng Zhang, Ping Pang, Ning Wang, Yu Bian, Baofeng Yang   +14 more
wiley   +1 more source

Integrated Care Models for Hepatitis C: Lessons From Southeast Asia and Sub-Saharan Africa. [PDF]

Open Forum Infect Dis
Abozait HJ, Hussein NR.
europepmc   +1 more source

Inherently chiral homo-heteracalixarenes: design and synthesis <i>via</i> an enantioselective intramolecular Sonogashira cross-coupling reaction. [PDF]

Chem Sci
Jiang YF, Zhang Y, Tong S, Zhu J, Wang MX.   +4 more
europepmc   +1 more source

Protein Energy Malnutrition: Opportunities for Cold Plasma Technologies

Food Frontiers, Volume 7, Issue 2, March 2026.
Protein energy malnutrition (PEM) is a major global health concern driven by biological, environmental, and nutritional factors, including gut microbiota imbalance and low protein intake. Cold atmospheric plasma technologies offer promising, sustainable solutions by improving food security, enhancing protein quality and absorption, and modulating gut ...
Karthika Prasad, Syamlal Sasi, Nina Recek, Janith Weerasinghe, Elena P. Ivanova, Igor Levchenko, Katia Alexander   +6 more
wiley   +1 more source

Mapping the TNFR2-targeting antibody patent landscape: Insights from macro trends to structural signatures. [PDF]

Hum Vaccin Immunother
Chen S, Chen Y, Zhang Y, Yao G, Cai H, Chen X, Hu Y.   +6 more
europepmc   +1 more source

The association of umbilical cord blood neurofilament light with non‐reassuring fetal status: A prospective observational study

International Journal of Gynecology &Obstetrics, Volume 172, Issue 3, Page 1491-1500, March 2026.
Abstract Objective Early detection of hypoxic–ischemic encephalopathy (HIE) in neonates is critical. We conducted a pilot cohort study to determine the feasibility of collecting umbilical cord blood samples for neurofilament light (NfL) and to assess the association of NfL with non‐reassuring fetal status and other cord biomarkers. We aimed to address (
David Zalcberg, Kaitlin Kramer, Emma Payne, Thomas Payne, Shreeya Marathe, Neha Mahajan, Ashly Liu, Jessica Barry, Andrew Duckworth, Mitchell Brooks, Bradley de Vries, Fernando Gonzalez‐Ortiz, Kaj Blennow, Henrik Zetterberg, Adrienne Gordon, Benjamin Moran, Helen J. Manning, Robert D. Sanders   +17 more
wiley   +1 more source

Combining cortical and spinal stimulation maximizes the improvement of gait after spinal cord injury. [PDF]

iScience
Drainville R, Bonizzato M, Burchielli D, Guay-Hottin R, Sheasby A, Martinez M.   +5 more
europepmc   +1 more source

Machine Learning Based Diagnostic Models for Hip and Knee Prosthetic Joint Infection: A Systematic Review

Journal of Orthopaedic Research, Volume 44, Issue 3, March 2026.
ABSTRACT Prosthetic joint infection (PJI) is a devastating complication that affects up to 1.7% of patients within 2 years following total hip arthroplasty (THA) or total knee arthroplasty (TKA). PJI is associated with significant patient morbidity, reduction in quality of life, prolonged hospitalisation, and healthcare expenditure.
Jaiden Nairne‐Nagy, Rudraksh Gupta, Boopalan Ramasamy, Lucian Bogdan Solomon, Stuart A. Callary   +4 more
wiley   +1 more source