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The Double-Icodextrin Dose Randomized Controlled Trial of a Double Icodextrin Dose for Older Patients on Incremental Continuous Ambulatory Peritoneal Dialysis [PDF]

open access: yesKidney International Reports
Introduction: Icodextrin enhances ultrafiltration (UF) in patients on peritoneal dialysis (PD) but is restricted to 1 bag/d, according to regulatory authorities.
Eric Goffin   +33 more
doaj   +2 more sources

Clinical benefits of icodextrin in peritoneal dialysis: Evidence from a multicenter, prospective, randomized controlled trial [PDF]

open access: yesJournal of International Medical Research
Background and objective Icodextrin is a novel, potentially advantageous peritoneal dialysis solution characterized by low glucose content and high molecular weight. This study aimed to compare the impact of icodextrin and glucose solutions on peritoneal
Yao Li, Chuanxiong Yang, Zhu Zhou
doaj   +2 more sources

Modelling of icodextrin hydrolysis and kinetics during peritoneal dialysis [PDF]

open access: yesScientific Reports, 2023
In peritoneal dialysis, ultrafiltration is achieved by adding an osmotic agent into the dialysis fluid. During an exchange with icodextrin-based solution, polysaccharide chains are degraded by α-amylase activity in dialysate, influencing its osmotic ...
Joanna Stachowska-Pietka   +5 more
doaj   +2 more sources

Development of a Novel Intraperitoneal Icodextrin/Dextrose Solution for Enhanced Sodium Removal [PDF]

open access: yesKidney Medicine
Rationale & Objective: Peritoneal dialysis (PD) solutions provide both clearance of uremic toxins and sodium and water. An intraperitoneal (IP) solution of icodextrin and glucose designed without the requirement for uremic toxin clearance could ...
Jennifer L. Asher   +17 more
doaj   +2 more sources

Icodextrin versus Glucose 2.5% on markers of hypervolemia and survival of patients undergoing automated peritoneal dialysis with an unplanned start: a randomized controlled trial [PDF]

open access: yesEinstein (São Paulo)
Objective: The efficacy of icodextrin versus glucose patients undergoing peritoneal dialysis remains unclear. The study was designed to compare the effects of once-daily long-dwell icodextrin versus glucose on markers of hypervolemia and survival among ...
Leonardo Sotello Azevedo   +7 more
doaj   +2 more sources

Can one long peritoneal dwell with icodextrin replace two short dwells with glucose? [PDF]

open access: yesFrontiers in Physiology
BackgroundDue to the slower dissipation of the osmotic gradient, icodextrin-based solutions, compared to glucose-based solutions, can improve water removal.
Joanna Stachowska-Pietka   +8 more
doaj   +2 more sources

Glycemic Control in Patients with Diabetes on Peritoneal Dialysis: From Glucose Sparing Approach to Glucose Monitoring [PDF]

open access: yesLife
Optimized glycemic management is crucial for controlling atherosclerosis and consequent cardiovascular morbidity in patients with diabetes. Due to the continuous glucose burden from glucose-containing peritoneal dialysis (PD) solutions, PD patients with ...
Aleksandra Kezić   +7 more
doaj   +2 more sources

Severe allergic rash induced by icodextrin: case report and literature review [PDF]

open access: yesFrontiers in Medicine
BackgroundIcodextrin is a type of peritoneal dialysis (PD) osmolyte that can be extended retention times (8–16 h) and may offer a viable alternative to conventional glucose dialysis solutions for PD patients.
Yiqi Huang   +7 more
doaj   +2 more sources

The impact of icodextrin on the outcomes of incident peritoneal dialysis patients. [PDF]

open access: yesPLoS ONE
ObjectiveThe aim of the study is to investigate the effects of icodextrin on the risks of death, technique failure and the first episode of peritonitis in peritoneal dialysis (PD) patients.MethodsFrom medical records of a medical center in Taiwan, a ...
I-Kuan Wang   +7 more
doaj   +2 more sources

Current Progress in Peritoneal Dialysis: A Narrative Review of Progress in Peritoneal Dialysis Fluid [PDF]

open access: yesLife
Peritoneal dialysis (PD) is a renal replacement therapy that removes solutes, electrolytes, and water via the infusion of dialysis fluid into the peritoneal cavity. However, the non-physiological composition of conventional PD fluids can cause peritoneal
Koji Hashimoto, Yuji Kamijo
doaj   +2 more sources

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