Results 51 to 60 of about 1,949 (176)

Transglutaminase 2 in human peritoneal dialysis‐related peritoneal injury

Physiological Reports, Volume 13, Issue 18, September 2025.
Abstract Patients undergoing long‐term peritoneal dialysis (PD) frequently develop peritoneal fibrosis and angiogenesis, leading to membrane dysfunction. Transglutaminase 2 (TG2) stabilizes the extracellular matrix against proteases. In an animal model, inhibition of TG2 reduced peritoneal fibrosis, angiogenesis, and inflammation.
Shunnosuke Kunoki, Masashi Ikeno, Hideki Tatsukawa, Yukinao Sakai, Hiroshi Kinashi, Keisuke Kamiya, Masafumi Suzuki, Masashi Mizuno, Makoto Yamaguchi, Hiroyuki Sasakura, Yuki Morioka, Masataka Banshodani, Mitsuhiro Tawada, Masato Iwabu, Takuji Ishimoto, Kosei Takeuchi, Kiyotaka Hitomi, Hideki Kawanishi, Yasuhiko Ito   +18 more
wiley   +1 more source

Prospective controlled randomized trial on prevention of postoperative abdominal adhesions by Icodextrin 4% solution after laparotomic operation for small bowel obstruction caused by adherences [POPA study: Prevention of Postoperative Adhesions on behalf of the World Society of Emergency Surgery]

Trials, 2008
Background Adhesive small intestine occlusion [ASIO] is an important cause of hospital admission placing a substantial burden on healthcare systems worldwide. Often times, ASIO is associated with significant morbidity and mortality.
D'Alessandro Luigi, Ercolani Giorgio, Lauro Augusto, Ansaloni Luca, Catena Fausto, Pinna Antonio   +5 more
doaj   +1 more source

Injectable and Sprayable Thermoresponsive Hydrogel with Fouling‐Resistance as an Effective Barrier to Prevent Postoperative Cardiac Adhesions

Advanced Science, Volume 12, Issue 23, June 20, 2025.
Postoperative cardiac adhesions lead to numerous difficulties in reoperation procedures. Here, a thermo‐responsive in situ formed hydrogel is shown to can reliably cover the wounds after a convenient spraying or injection and significantly reduce adhesion formation in primary and recurrent cardiac injury adhesion models.
Kun Shi, Tao Li, Xulin Hu, Wen Chen, Yan Yu, Zhongwu Bei, Liping Yuan, Qi Tong, Jiafeng Liu, Qiang Fan, Yongjun Qian, Zhiyong Qian   +11 more
wiley   +1 more source

Severe cutaneous hypersensitivity to icodextrin in a continuous ambulatory peritoneal dialysis patient [PDF]

, 2006
Icodextrin, a glucose polymer, is widely used as an alternative to glucose as the osmotic agent in peritoneal dialysis (PD). We describe a case of a continuous ambulatory peritoneal dialysis patient who developed severe cutaneous hypersensitivity after ...
박형천, 하성규
core  

A Dual‐Layer Hydrogel Barrier Integrating Bio‐Adhesive and Anti‐Adhesive Properties Prevents Postoperative Abdominal Adhesions

Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.
A new dual‐layer hydrogel barrier for preventing postoperative abdominal adhesions is developed. The inner layer, consisting of polyethyleneimine (PEI) and thioctic acid (TA), enhanced adhesion to moist tissues. The outer layer combines zwitterionic, thermoresponsive hyaluronic acid with anti‐inflammatory epigallocatechin gallate (EGCG) and forms a ...
Mena Asha Krishnan, Olawale A. Alimi, Mitchell Kuss, Tiffany N Razabdouski, Erika A Eksioglu, Bin Duan, Bo Liu   +6 more
wiley   +1 more source

Longitudinal relationships between fluid status, inflammation, urine volume and plasma metabolites of icodextrin in patients randomized to glucose or icodextrin for the long exchange

, 2008
Background. Randomized trials have shown that icodextrin reduces the volume of extra-cellular fluid (ECFv) with variable effects on residual renal function.
Lindholm, Bengt, Bosselmann, Hans-Peter, Lopez, Elvia Garcia, Heimburger, Olof, Johansson, Ann Catherine, Simonsen, Ole, Donovan, Kieron, Williams, Paul, Filho, Jose C. Divillo, Davenport, Andrew, Tranaeus, Anders, Davies, Simon J., Woodrow, Graham, Plum, Jorg, Lund University., Simonsen, Ole,   +15 more
core   +1 more source

Ultrafiltration trough peritoneal dialysis in refractory congestive heart failure patients: one center experience

Turkish Journal of Internal Medicine, 2020
Background: Hypervolemia is an important consequence of heart failure (HF) that leads to poor quality of life and frequent hospitalizations. Ultrafiltration (UF) with dialysis is an option for HF patients who are resistant or inappropriate for diuretics.
Mehmet Fethullah Aydın, Ayşegül Oruç, Alparslan Ersoy, Abdulmecit Yildiz, Mahmut Yavuz, Kamil Dilek, Mustafa Güllülü   +6 more
doaj   +1 more source

Miniaturized Optical Glucose Sensor Using 1600–1700 nm Near‐Infrared Light

Advanced Sensor Research, Volume 4, Issue 3, March 2025.
The capability to detect glucose levels non‐invasively taking into account interference from water is demonstrated. A glucose‐informative waveband in 1600–1700 nm is demonstrated with a miniaturized optical sensor successfully detecting glucose levels in the physiological range, showing the potential for futuristic non‐invasive glucose monitoring ...
Mingjie Yang, Shanmuga Sundar Dhanabalan, Md Rokunuzzaman Robel, Litty Varghese Thekkekara, Sanje Mahasivam, Md Ataur Rahman, Sagar Borkhatariya, Suvankar Sen, Sumeet Walia, Sharath Sriram, Madhu Bhaskaran   +10 more
wiley   +1 more source

Early quality of life benefits of icodextrin in peritoneal dialysis

, 2002
Early quality of life benefits of icodextrin in peritoneal dialysis.BackgroundThe impact of new therapies on patient quality of life (QOL) is emerging as an important indicator of the value of these therapies.
Wolfson, Marsha, Holt, Robert, Guo, Amy
core   +1 more source

Additional file 2: of Comparison of clinical effects between icodextrin and glucose solutions on outcomes of peritoneal dialysis: systematic review and meta-analysis of randomized controlled trials

, 2020
Figure S1. Effects of icodextrin on urine volume. Figure S2. Effects of icodextrin on residual renal function. Figure S3. Effects of icodextrin on peritoneal function. Figure S4. Effects of icodextrin on peritonitis. Figure S5.
Munekazu Ryuzaki (7384904), Emi Fujikura (8304627), Kimio Watanabe (496706), Hidetomo Nakamoto (4987481), Yasushi Tsujimoto (4664440), Hidemichi Yuasa (7384901), Takayuki Fujii (617435), Atsuhiro Kanno (8304624), Yasuhiko Ito (588831)   +8 more
core   +1 more source