Results 111 to 120 of about 543,737 (387)

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Content validity of a novel patient-reported and observer-reported outcomes assessment to evaluate ocular symptoms associated with infectious conjunctivitis in both adult and pediatric populations

Health and Quality of Life Outcomes, 2019
Background Acute infectious conjunctivitis is a common condition most frequently caused by viruses or bacteria. Clinical outcome assessments have been used to assess signs and symptoms of bacterial and viral conjunctivitis, but have not been evaluated ...
Sujata P. Sarda, Marie De La Cruz, Emuella M. Flood, Magdalena Vanya, David G. Hwang, Christopher N. Ta, Abhijit Narvekar   +6 more
doaj   +1 more source

Comparative Study of Icon Design for Mobile Application

Journal of Physics: Conference Series, 2020
Icons are widely used in mobile applications as visual displays that can assist the acquisition and understanding of information. An icon creates better visual perception with the ability to communicate meaning.
Norazlina Kamarulzaman, Norasikin Fabil, Zulkifly Mohd Zaki, Roesnita Ismail   +3 more
semanticscholar   +1 more source

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

FEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai, Richard J. McDowell, Robert J. Lucas   +2 more
wiley   +1 more source

Students’ Attitudes and Perceptions on Xenophobia: A Study of a University in Durban

Journal of Student Affairs in Africa, 2019
The recurrence of xenophobic violence in South Africa has been attributed to the proliferation of antimigrant sentiments that stems from social, political, economic and cultural misconceptions and cleavages.
Olubunmi Damilola Akande, Hilary Jephat Musarurwa, Sylvia Blanche Kaye Blanche Kaye   +2 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Talking with pictures: Exploring the possibilities of iconic communication [PDF]

, 1993
As multimedia computing becomes the order of the day, so there is a greater need to understand and to come to terms with the problems of visual presentation.
Beardon, Colin, Dormann, Claire, Mealing, Stuart, Yazdani, Masoud   +3 more
core   +2 more sources

ICON‐A, The Atmosphere Component of the ICON Earth System Model: II. Model Evaluation

Journal of Advances in Modeling Earth Systems, 2018
We evaluate the new icosahedral nonhydrostatic atmospheric (ICON‐A) general circulation model of the Max Planck Institute for Meteorology that is flexible to be run at grid spacings from a few tens of meters to hundreds of kilometers.
T. Crueger, M. Giorgetta, R. Brokopf, M. Esch, S. Fiedler, C. Hohenegger, L. Kornblueh, T. Mauritsen, C. Nam, A. K. Naumann, K. Peters, S. Rast, E. Roeckner, M. Sakradzija, H. Schmidt, J. Vial, R. Vogel, B. Stevens   +17 more
semanticscholar   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source