Results 121 to 130 of about 206,500 (292)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

icon: web icons for rmarkdown

open access: yes, 2018
🔗Icons in R Icons can be added to your R Markdown documents using short prefixes which identify the font’s library.fa: Font Awesomeai: Academiconsii: ionicons For example, `r icon::fa("rocket")` can be used to add the rocket icon from Font Awesome.
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Multi-part icons in the collection of the National Museum of History of Moldova. Visual hagiography

open access: yesTyragetia, 2020
In the collection of the National Museum of History of Moldova there are several icons that differ in their iconographic composition. On one icon panel there are several separate images at once, representing well-known icons or images of saints, or ...
Adelaida Chiroşca
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

The Theology of the Icon

open access: yesSt Andrews Encyclopaedia of Theology
The Christian icon – from eikon, the Greek word for ‘image’ – has been part of liturgical worship from the early centuries of the Christian era, and sometimes also a subject of theological debate.
Aidan Hart
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Composite video and graphics display for camera viewing systems in robotics and teleoperation [PDF]

open access: yes, 1993
A system for real-time video image display for robotics or remote-vehicle teleoperation is described that has at least one robot arm or remotely operated vehicle controlled by an operator through hand-controllers, and one or more television cameras and ...
Diner, Daniel B., Venema, Steven C.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Датиране на икони чрез анализ на изображения на дървени елементи заснети с цифров фотоапарат

open access: yesБългарско е-Списание за Археология, 2019
The precise dating of wooden elements from historical sites is possible with dendrochronological methods. Usually tree-ring cores are extracted with increment borers and then analyzed.
Momchil Panayotov   +2 more
doaj  

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