Results 131 to 140 of about 63,854 (262)

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

Advanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li, Simin Chen, Huijuan Hu, Shiyao Wu, Jingnan Wang, Kai Sun, Chenxi Peng, Suling Liu, Shuoyang Zhang, Yu Kuang, Wei Chen, Qian Qiu, Liuqin Liang, Yu Wen, Hanshi Xu, Youjun Xiao   +15 more
wiley   +1 more source

Trace Element Imbalance and Redox-Relevant Serum Profile in Hemodialysis: A Validated Multielement ICP-MS Study. [PDF]

Antioxidants (Basel)
Valderrama-Sanz S, Tortosa-Carreres J, Molina-Gasset R, Todolí-Torró JL.   +3 more
europepmc   +1 more source

Chemically Gradient Ordered Nanodomains Enable Large Tensile Ductility in Gigapascal Lightweight Refractory High‐Entropy Alloys

Advanced Science, EarlyView.
A high‐strength lightweight refractory high‐entropy alloy achieves extraordinary ductility owing to the introduction of coherent chemically gradient ordered nanodomains (CGONs). The CGONs not only serve as effective barriers to dislocation motion (strengthening) but also significantly promote dislocation nucleation and multiplication (ductilizing) upon
Wei Zhang, Dingshun Yan, Yong Zhang, Zhiming Li   +3 more
wiley   +1 more source

Novel magnetic nanosorbent graphene oxide-based for the automatic and simultaneous determination of arsenic and antimony by MSPE-FI-HG-ICP-MS. [PDF]

Mikrochim Acta
Morales-Benítez I, Doblado-Onieva Á, Sánchez-Trujillo I, Vereda-Alonso C, López Guerrero MM, Vereda Alonso EI.   +5 more
europepmc   +1 more source

In Situ Reconstructed Crystalline–Amorphous CuNi Nanotubes Unifying Activity and Stability for Oxygen Evolution

Advanced Science, EarlyView.
Controlled electrochemical reconstruction creates a crystalline–amorphous CuNi nanotube that unifies catalytic activity and durability for alkaline oxygen evolution. The conductive metallic core and active amorphous oxide shell work synergistically to deliver low overpotential and exceptional stability exceeding 1000 h, offering a new strategy for ...
Shi‐Yu Zhu, Han Gao, Meng Li, Ling‐Rui Wang, Tian‐Yu Xia, Wei‐Di Liu, Xiao‐Lei Shi, Hai‐Zhong Guo, Zhi‐Gang Chen   +8 more
wiley   +1 more source

Mapping the global origins of soybean: a study using ICP-MS and chemometrics. [PDF]

NPJ Sci Food
Aparicio-Muriana MM, Hong Y, Chilaka CA, Quinn B, Montes-Niño AM, Birse N, Elliott CT.   +6 more
europepmc   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Metallomic Aspects of Stroke and Recovery: ICP-MS Study with Chemometric Analysis. [PDF]

Molecules
Rospond B, Matusiak A, Stolarczyk EU, Piotrowska J, Pomierny B, Krzyżanowska W, Szafrański PW, Dorożyński P.   +7 more
europepmc   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source