Results 171 to 180 of about 32,912 (282)

Unlocking the serine mischarging paradox and inhibiting lactyltransferase activity of AlaRS by a single-point mutation. [PDF]

Nucleic Acids Res
Park W, Son SY, Yi J, Cha S, Moon H, Kim M, Ji S, Yu W, Sung C, Cha SS, Hahn JS.   +10 more
europepmc   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Real-world comparison of BTK inhibitors and lenalidomide as first-line maintenance in primary CNS lymphoma: a multi-center retrospective study. [PDF]

J Neurooncol
Chang X, He Z, Wang H, Zhu H, Guo Y, Zou D, Zhao Z, Song T, Hu R, Ni J, Zhao H, Hui W, Liu Z, Li Z, Zhang W, Zhou D, Zhang Y, Sun W.   +17 more
europepmc   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Parvimonas micra-polarized M2-like tumor-associated macrophages accelerate colorectal cancer development via IL-8 secretion. [PDF]

Anim Cells Syst (Seoul)
Nguyen DK, Kang MJ, Oh SJ, Park HJ, Kim SH, Yu JH, Lee Y, Lee HS, Yang JW, Seo Y, Ahn JS, Kim HS.   +11 more
europepmc   +1 more source

Departmental investment strategy 2005-08: July 2005 [PDF]

core  

Synergistic Interplay of Acceptor and Isovalent Co‐Doping on BaZrO3‐Based Proton Conducting Oxides: A First‐Principles Study

Advanced Science, EarlyView.
Acceptor and isovalent co‐doping effects on hydration in BaZrO3 proton conductors are systematically investigated using first‐principles calculations. Acceptors enhance hydration by modulating oxygen vacancy formation, whereas isovalent dopants enhance hydration by stabilizing protons via increased A‐site cation–proton distances.
Yonghun Shin, Kyung‐Yeon Doh, June Ho Lee, Shin Hyun Kim, Donghwa Lee   +4 more
wiley   +1 more source

Commensal microbe-derived butyrate enhances T follicular helper cell function to boost mucosal vaccine efficacy. [PDF]

Microbiome
Ko H, Kim CJ, Choi S, Noh J, Kim SW, Lee J, Byun S, Lee H, Park JC, Park HE, Sharma A, Park M, Park J, Lee CG, Cha KH, Im SH.   +15 more
europepmc   +1 more source

Fabrication of High‐Density Multimodal Neural Probes Based on Heterogeneously Integrated CMOS

Advanced Science, EarlyView.
A chiplet‐based methodology democratizes active neural probe development on standard bulk CMOS services. This yields the first probe combining high‐density electrophysiology (416 electrodes) with calcium imaging (832 photodiodes) and complete on‐chip signal processing across 13 shanks.
Ju Hee Mun, Miji Kim, Wooyeon Shin, Yongjun Park, Kanghwan Kim, Il‐Joo Cho, Jae Won Shim, Min Soo Kim, Sunwoo Lee, Jeongjin Kim, Changhyuk Lee   +10 more
wiley   +1 more source

Cannabigerol Exerts <i>In Vivo</i> and <i>In Vitro</i> Anti-Inflammatory Effects via Inhibition of the MAPK and NF-κB Pathways. [PDF]

J Microbiol Biotechnol
Kim JH, Hong M, Han JH, Ryu BR, Lim JD, Kim KC, Kim CH, Lee SU, Kwon TH.   +8 more
europepmc   +1 more source