Results 91 to 100 of about 346,338 (269)

Targeting eEF1A1 With Baicalein to Block eEF1A1/Prdx4 Interaction for Treating Sepsis‐Mediated Lung Injury

Exploration, EarlyView.
Targeting eEF1A1 with baicalein disrupts the eEF1A1‐Prdx4 interaction to prevent RNF14‐mediated ubiquitination and degradation of Prdx4. This stabilizes Prdx4 to suppress NF‐κB, thereby alleviating sepsis‐induced acute lung injury. ABSTRACT Sepsis is a systemic inflammatory response syndrome triggered by an uncontrolled host response to infection ...
Jing Chang, Hui‐Lin Zhang, Qi‐Meng Zhu, Si‐Wen Hui, Xin‐Rong Xu, Mahmood Brobbey Oppong, Yan‐Li Feng, Juan Zhang, Cheng‐Peng Sun, Feng Qiu   +9 more
wiley   +1 more source

Ventilatory pressure parameters impact the association between acute gastrointestinal injury and all-cause mortality in mechanically ventilated patients

Scientific Reports
Acute gastrointestinal injury (AGI) is common in mechanically ventilated (MV) patients, but the potential association between ventilatory pressure parameters and AGI grade and their impact on mortality remains unclear.
Shao Ziqiang, Li Jiale, Sun Renhua, Wu Aiping, Ni Yin, Liu Jingquan, Guo Feng, Ying Lijun, Ge Guoping, Ding Aijun, Shi Yunchao, Liu Changwen, Xu Lei, Jiang Ronglin, Lu Jun, Lin Ronghai, Zhu Yannan, Wu Weidong, Xie Bo, Hu Bangchuan   +19 more
doaj   +1 more source

Flexible wearable electronics for cardiovascular monitoring from surface signals to deep physiological insights

FlexMat, EarlyView.
This review organizes flexible wearable electronics for cardiovascular monitoring into four interconnected information layers: surface electrophysiology, hemodynamic sensing, vascular imaging, and biofluid biomarker analysis. This framework clarifies how electrical rhythm, vascular loading, structural and flow‐related features, and biochemical states ...
Qiao Chen, Hongwen Chen, Yuanyuan Li, Pingan Yang, Rui Li, Zhihao Zhou   +5 more
wiley   +1 more source

ICU requirements

European Journal of Trauma and Emergency Surgery
Abstract This section outlines the essential requirements for managing trauma patients in ICUs across Europe. It emphasizes the need for ICU accreditation at the highest national level and highlights criteria, including staffing, equipment, training programmes, protocols, and documentation for quality control.
Balogh, Zsolt, Hildebrand, Frank
openaire   +3 more sources

Swallowing‐Related Quality of Life After Carotid Body Tumor Resection: A Longitudinal Trajectory Analysis

Head &Neck, EarlyView.
ABSTRACT Objectives To identify longitudinal swallowing‐related QoL trajectories after carotid body tumor (CBT) resection and explore associated characteristics. Methods A prospective study assessed swallowing‐related QoL using the MD Anderson Dysphagia Inventory at nine timepoints from preoperation to 12 months postdischarge.
Pan Chen, Qiao‐Dan Lu, He‐Jing Liang, Ming‐Hua Guo, Jia‐Pin Chen, Chun‐Xu Yang, Guang‐Chao Gu, Lei Wang, Yue‐Hong Zheng   +8 more
wiley   +1 more source

“Thinking Out Loud” and “Pivoting on the Fly”—An Empirical Review and Critical Incident Study of How Physicians Engage in Incidental Learning Amidst Complexity

Human Resource Development Quarterly, EarlyView.
ABSTRACT This study explores incidental learning among physicians navigating uncertainty during the COVID‐19 pandemic. Using a constructivist research design, we conducted a literature review of 13 empirical studies on incidental learning in complexity and analyzed critical incident interviews with 12 emergency medicine and intensive care physicians ...
Henriette Lundgren, Karen E. Watkins, Victoria J. Marsick, Dimitrios Papanagnou, Urvashi Vaid   +4 more
wiley   +1 more source

Anti‐NMDA receptor autoimmune encephalitis associated with ovarian teratoma: A case series and literature review

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 23-30, April 2025.
Abstract Autoimmune encephalitis is a group of disorders characterized by symptoms of dysfunction of the limbic and extra‐limbic systems that occur in association with antibodies against intracellular antigens, synapses, or proteins located on the surface of nerve cells. Anti‐NMDA (N‐methyl‐D‐aspartate) receptor encephalitis was first described in 2007
Pham Ba Nha, Nguyen Phuong Tu, Nguyen Viet Ha, Duong Thi Thu Hien, Nguyen Thi Thu Phuong, Nguyen Anh Son, Nguyen Tien Hoang   +6 more
wiley   +1 more source

Using indirect calorimetry in place of fixed energy prescription was feasible and energy targets were more closely met: do not forget an important limitation

Critical Care, 2020
Patrick M. Honore, Leonel Barreto Gutierrez, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, David De Bels   +6 more
doaj   +1 more source

Perinatal outcomes in normotensive versus hypertensive HELLP syndrome

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare maternal and neonatal outcomes between women with hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome with and without associated hypertension. Methods This was a retrospective cohort study at a tertiary university‐affiliated medical center including all singleton HELLP cases >24 weeks gestation (January ...
Matan Anteby, Keren‐Or Wertheimer, Omri Dominsky, Liran Hiersch, Yariv Yogev   +4 more
wiley   +1 more source

No dose adjustment of tigecycline is necessary during continuous renal replacement therapy: we are not sure

Critical Care, 2020
Patrick M. Honore, Cristina David, Luc Kugener, Sebastien Redant, Rachid Attou, Andrea Gallerani, David De Bels   +6 more
doaj   +1 more source