Results 111 to 120 of about 346,338 (269)

Study find that COVID ARDS was associated with a low risk for possible or proven PCP: still true after dexamethasone use

open access: yesCritical Care, 2022
Patrick M. Honore   +8 more
doaj   +1 more source

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

open access: yesiMeta, EarlyView.
Severe Klebsiella pneumoniae pneumonia combines intense inflammation with failure to control infection, yet the cellular basis is unclear. Using a severity‐focused single‐cell atlas of 708,894 peripheral blood mononuclear cells from 100 individuals, complemented by plasma protein measurements and flow cytometry, we show that disease severity redirects ...
Hongquan Chen   +23 more
wiley   +1 more source

Biomarkers to delineate bacteremia from candidemia remain a challenging issue

open access: yesCritical Care, 2020
Patrick M. Honore   +5 more
doaj   +1 more source

The Emotional Allodynia Questionnaire: Preliminary Validation and Clinical Phenotyping in Fibromyalgia

open access: yesJournal of Pain Research
Alberto Corriero,1 Mariateresa Giglio,1 Alfonso Pilolla,1 Filomena Galdini,1 Olmina Mucci,1 Miriana Vurro,1 Fara Fornarelli,1 Cinzia Di Venosa,1 Paolo Trerotoli,2 Filomena Puntillo1 1Department of Interdisciplinary Medicine – Pain and ICU Section ...
Corriero A   +9 more
doaj  

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

open access: yesInterdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li   +15 more
wiley   +1 more source

Procalcitonin to allow early detection of sepsis and multiple organ failure in severe multiple trauma: beware of some confounders

open access: yesCritical Care, 2020
Patrick M. Honore   +5 more
doaj   +1 more source

Deniers and Compliers: Unpacking the Heterogeneous Effectiveness of U.S. Stay‐at‐Home Mandates During the COVID‐19 Pandemic

open access: yesJournal of Applied Econometrics, EarlyView.
ABSTRACT While existing work shows COVID‐19 stay‐at‐home (SAH) policies decreased mobility on average, we lack evidence regarding heterogeneity in policy effectiveness across US counties. To uncover potential heterogeneity, we implement a novel two‐stage approach.
James Sears   +5 more
wiley   +1 more source

Risk of harlequin syndrome during bi-femoral peripheral VA-ECMO: should we pay more attention to the watershed or try to change the venous cannulation site?

open access: yesCritical Care, 2020
Patrick M. Honore   +6 more
doaj   +1 more source

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