Results 121 to 130 of about 346,338 (269)

WIse CHoices in the ICU (WICH-ICU): Protocol and Statistical Analysis Plan for a Stepped-Wedge Cluster Randomized Trial of Choosing Wisely Interventions in Swedish Intensive Care Units. [PDF]

Acta Anaesthesiol Scand
Larsson E, Valadkhani A, Eriksson J, Svensk E, Hammarskjöld F, Castegren M, Bentzer P, Nielsen N, Svennerholm K, Eriksson M, Bell M.   +10 more
europepmc   +1 more source

Compare Serum VCAM‐1, NSE, Procalcitonin in Predict Sepsis Induced Encephalopathy in Septic Patients

Journal of Clinical Laboratory Analysis, EarlyView.
Serum VCAM‐1 is associated with septic encephalopathy in the first 7 days of sepsis. NSE and procalcitonin were not associated with septic encephalopathy. ABSTRACT Background Sepsis‐associated encephalopathy (SAE) is a common complication of severe sepsis. Increased concentration of Vascular Cell Adhesion Molecule 1 (VCAM‐1) is associated with SAE in a
Chun‐Fu Lin, Cheng‐Hsien Lu, Chih‐Min Su   +2 more
wiley   +1 more source

Characteristics and Outcomes of Patients Referred but Declined for ICU Admission in a Resource-Limited Setting in South Africa. [PDF]

Crit Care Explor
Anesi GL, Ndadane N, Invernizzi J, Alladeen SA, Ramkillawan A, Savarimuthu SM, Wise RD, Smith MTD, Farina Z.   +8 more
europepmc   +1 more source

Unfractionated Heparin and Low‐Molecular‐Weight Heparin in Sepsis: Anti‐Inflammatory and Anticoagulant Effects Versus No Anticoagulation—A Propensity Score‐Matched Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
This propensity score‐matched study compared unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) in 1362 sepsis patients, finding that both significantly improved survival without increasing 90‐day bleeding risk. However, their therapeutic mechanisms differed: UFH demonstrated broader anti‐inflammatory effects by reducing IL‐6, IL‐8 ...
Peili Chen, Yi Yao, Bing Zhao, Yuan An, Jian Jiang, Li Ma, Enqiang Mao, Yihui Wang   +7 more
wiley   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Association of IFN‐γ +874 T/A Polymorphism With COVID‐19 Susceptibility, Severity, and Inflammatory Response: A Case–Control Study From Southern Iran

Journal of Clinical Laboratory Analysis, EarlyView.
Graphical abstract illustrating the association between IFN‐γ +874 T/A polymorphism and COVID‐19 outcomes. TA and AA genotypes are linked to increased susceptibility, higher inflammatory markers (notably IL‐6), greater disease severity, and longer hospitalization.
Nasir Arefinia, Bahman Aghcheli, Seyed Mohammad Ali Hashemi, Zohreh‐al‐sadat Ghoreshi, Emad Behboudi   +4 more
wiley   +1 more source

Model for End‐Stage Liver Disease/Pediatric End‐Stage Liver Disease exception policy and outcomes in pediatric patients with hepatopulmonary syndrome requiring liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End‐Stage Liver Disease (MELD)/Pediatric End‐Stage Liver Disease (PELD) exception points for waitlist prioritization in the United States based on criterion developed for adults.
Muhammad H. Raza, Yong Kwon, Pierre Kobierski, Asish C. Misra, Angelina Lim, Cameron Goldbeck, Kambiz Etesami, Rohit Kohli, Juliet Emamaullee   +8 more
wiley   +1 more source

Indirect ICU Admissions From an Australian Emergency Department: Risk Factors and Outcomes. [PDF]

Emerg Med Australas
McLennan D, Reid C, Martin R, Olive S, Eslick G.   +4 more
europepmc   +1 more source

METTL7B Expression in Sepsis: Association With Disease Severity and 28‐Day Mortality

Journal of Clinical Laboratory Analysis, EarlyView.
This prospective cohort study demonstrates that whole blood METTL7B expression is significantly elevated in sepsis patients upon ICU admission and independently associates with disease severity and 28‐day mortality. METTL7B alone predicted 28‐day mortality with an AUC of 0.779, and its combination with dynamic SOFA score and PCT achieved the highest ...
Yuxuan Zhang, Yonghua Wang, Mengjiao Yang, Dan Huang   +3 more
wiley   +1 more source

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

Liver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono, Riccardo De Carlis, Alessandro Gambella, Francesca Farnesi, Alice Podestà, Andrea Lauterio, Francesco Tandoi, Luciano De Carlis, Renato Romagnoli   +8 more
wiley   +1 more source