Results 121 to 130 of about 6,962,642 (291)
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
AMČR - archeologický záznam C-9122836A
Stav: 3Lokalizace/okolnosti: Křižovatka Divišovy a Šimkovy ...
https://api.aiscr.cz/id/OS-005362 +1 more
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SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
AMČR - archeologický záznam C-9100686A
Stav: 3Lokalizace/okolnosti: Vrch Radiš (kóta 752), 1100 m západně od středu obce, prostor vrcholové plošiny.Souhrn/upřesnění: Povrchový sběr a drobná mikrosondáž v areálu známého hradiště za účelem ověření jeho stáří.
https://api.aiscr.cz/id/ORG-000125 +1 more
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[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich +19 more
wiley +1 more source
AMČR - archeologický záznam C-9149385A
Stav: 3Lokalizace/okolnosti: Trať U mohyl (též Bráníky nebo Chlívec), SV od kóty 436, ppč. 1924/1.Souhrn/upřesnění: Lesní oddělení 344 d 1, lesní správa Sobědraž, S od cesty: 1 mohyla prokopaná B. Dubským. Lesní oddělení 344 f, J.
https://api.aiscr.cz/id/OS-007301 +1 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
AMČR - archeologický záznam C-9159844A
Stav: 3Lokalizace/okolnosti: Čertova ruka, ppč.
https://api.aiscr.cz/id/OS-006512 +1 more
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Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
AMČR - archeologický záznam C-9121802A
Stav: 3Lokalizace/okolnosti: S od vrchu Vinice, V břeh rybníka ...
https://api.aiscr.cz/id/ORG-000094 +1 more
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