Results 141 to 150 of about 6,962,642 (291)

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

AMČR - archeologický záznam C-9139816A

open access: yes
Stav: 3Lokalizace/okolnosti: Mikrolokalita VIII – ppč. 633, 634, 648 (dle pozemkového katastru)
https://api.aiscr.cz/id/OS-006011   +1 more
core  

PMX-CovEval: A Framework Including a Simulated Pharmacokinetic Database for Covariate Model Building Methods Benchmarking. [PDF]

open access: yesCPT Pharmacometrics Syst Pharmacol
Karlsen M   +6 more
europepmc   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

AMČR - archeologický záznam C-9117917A

open access: yes
Stav: 3Lokalizace/okolnosti: Poloha Louňov, ppč. 601 a 602. Nyní k.ú. Dívčice, ppč. 1324.Souhrn/upřesnění: Sběry z více sezón (1958 - Sakař, 1960 - Fiedler, 1964 - Beneš, 1973 - Michálek).
https://api.aiscr.cz/id/OS-006986   +1 more
core  

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

AMČR - archeologický záznam C-9151284A

open access: yes
Stav: 3Lokalizace/okolnosti: Lochotínská ul. čp. 26, ppč. 83, místo bývalého dvora F. Kasla, u kanceláří Zahradnických podniků. Podnět: stavba.Souhrn/upřesnění: R. 1964 prozkoumána hrčířská pec ze 14. stol. narušující hradištní jámu.
https://api.aiscr.cz/id/ORG-000184   +1 more
core  

Gratitude in ID and a Challenge. [PDF]

open access: yesOpen Forum Infect Dis
Graf PJ, Hartzell JD.
europepmc   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi   +8 more
wiley   +1 more source

AMČR - archeologický záznam C-9131424A

open access: yes
Stav: 3Lokalizace/okolnosti: Návrší Skalka, Z od silnice Velim-Nová Ves I, J od Nouzovského potoka, dříve k.ú. Nová Ves ppč. 238/5, 6. Podnět: stavba.Souhrn/upřesnění: Průběh příkopů a dalších objektů byl pokusně zjišťován pomocí elektrické odporové ...
https://api.aiscr.cz/id/OS-007624   +1 more
core  

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