Results 121 to 130 of about 456,135 (334)

INEL Spray-forming Research [PDF]

open access: yes, 1992
Spray forming is a near-net-shape fabrication technology in which a spray of finely atomized liquid droplets is deposited onto a suitably shaped substrate or mold to produce a coherent solid.
Key, James F., Mchugh, Kevin M.
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Reliability and Validity for Measuring Active Hip Rotation with the Clinometer Smartphone Application™

open access: yesJournal of Rehabilitation Sciences and Research, 2019
Background: Accurate range of motion (ROM) assessment is an essential component of clinical practice to identify underlying deficits at the hip joint. Hip joint active ROM has been measured by goniometric methods in the clinical setting.
Emilie Miley   +5 more
doaj  

A Review of the Research and Development of Brayton Cycle Technology in Nuclear Power Applications with a Focus on Compressor Technology

open access: yesEnergies
This study reviews the integration of Brayton Cycle (BC) systems in nuclear power generation, emphasizing their potential to enhance thermal efficiency and operational flexibility over traditional Rankine Cycle (RC) systems.
Aidan Rigby   +5 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Modelling and analysis of nuclear reactor system coupled with a liquid metal battery

open access: yesThe Journal of Engineering
Traditionally, nuclear power plants in the U.S. provide baseload power to the power grid because they have less flexibility for ramping their output power than natural gas peaking plants.
Amey Shigrekar   +4 more
doaj   +1 more source

Extraction of Terpenoids from Pine Needle Biomass Using Dimethyl Ether

open access: yesSeparations
Pine needles are an industrial feedstock for extracts used in a variety of applications, but conventional extraction methods often result in a degradation of the terpenoid compounds that naturally occur in loblolly pine (Pinus taeda). Separation of these
Gary S. Groenewold   +5 more
doaj   +1 more source

Windsor and Its Discontents: State Income Tax Implications for Same-Sex Couples [PDF]

open access: yes, 2014
In United States v. Windsor, the Supreme Court struck down section three of the federal Defense of Marriage Act. Shortly thereafter, the Internal Revenue Service issued a ruling under which all married same-sex couples will be treated as married for ...
Mir, Haniya H.
core   +1 more source

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