Results 81 to 90 of about 422,338 (292)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Annual average daily traffic forecasting using different techniques [PDF]

Transport, 2006
This paper describes annual average daily traffic (AADT) forecasting for the Lithuanian highways using a forecasting method used by Idaho Department for Transportation, growth factor, linear regression and multiple regression.
T. Šliupas
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Developing A Digital Twin of a TRUEX Extraction Process that Enables Non-proliferation and Safeguards Monitoring through Optical Spectroscopy and Machine Learning [version 1; peer review: 1 approved, 2 approved with reservations]

Nuclear Science and Technology Open Research
Background The recycling of spent fuel can increase the longevity and decrease the waste footprint associated with the nuclear fuel cycle. However, nuclear fuel reprocessing introduces the risk of proliferation of fissile material.
Justin T. Cooper, Ramedy Flores, Addyson Barnes, Eduardo Trevino, Kathrine Jesse, Kolton Heaps, Adam J. Pluth, Ashley Shields, Jaren Brownlee   +8 more
doaj   +1 more source

Class Notes [PDF]

, 2006
News about Linfield ...
Davis, Laura, Linfield Magazine Staff, Thompson, Beth Rogers   +2 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Does Outdoor Recreation Decrease Stress? Investigating the Physiological Responses of Outdoor Recreation in Idaho [PDF]

, 2016
This poster was presented at the 2016 Idaho EPSCoR Annual Meeting, October 19-21, in Couer d\u27Alene ...
Demps, Kathryn, Heath, Julie, Opdahl, Ellie   +2 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

DETERMINING THE EFFECTS OF LAND CHARACTERISTICS ON FARMLAND VALUES IN SOUTH-CENTRAL IDAHO [PDF]

This study focused on evaluating the effects of different attributes that impact irrigated farmland values in South-central Idaho. Results indicate that study area farmland values are largely determined by agricultural productivity (profiability) related
Hamilton, Joel R., Nelson, James R., Vasquez, Orestes, Wright, Khaliela S.   +3 more
core   +1 more source

Confucius in the Catalog: Enhancing the Discoverability of a Campus Collection [PDF]

, 2019
This article details the multi-year process of adding a 3,200 item campus collection to a university library’s catalog. The collection, housed outside of the library itself, belongs to the university’s Confucius Institute (CI).
Attebury, Ramirose Ilene
core   +1 more source