Results 11 to 20 of about 24,661 (222)
Integrated Multi-Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC. [PDF]
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Zhang N +18 more
europepmc +2 more sources
Interaction Design @ IDC Limerick [PDF]
Interaction Design @ IDC ...
Liam Bannon, Luigina Ciolfi
doaj +3 more sources
Commentaries on IDC Theory in practice
A total of seven scholars were invited to provide commentaries to the paper on the IDC experimental school in Taiwan. We collated their commentaries below, arranged in alphabetical order of the authors’ last names. We acknowledge and appreciate the excellent points raised by the commentators regarding the current and future ...
Wenli Chen 0004 +6 more
openaire +2 more sources
Development of a Nomogram-Based Clinical Estimation Model for Pathological Upstaging in Patients With Preoperative Ductal Carcinoma In Situ. [PDF]
ABSTRACT Preoperative diagnosis of ductal carcinoma in situ (DCIS) may be followed by pathological upstaging to invasive ductal carcinoma (IDC) upon surgical excision, a discrepancy that significantly impacts surgical planning and decisions regarding sentinel lymph node biopsy (SLNB).
Chen YH +5 more
europepmc +2 more sources
Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer [PDF]
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Alexandrou S +17 more
europepmc +2 more sources
The objective of this study was to investigate the clinical significance and roles of tumor progression locus 2 (TPL2) and peptidyl-prolyl cis–trans isomerase 1 (Pin1) in the occurrence and development of breast invasive ductal carcinoma (IDC ...
Qin Yu +4 more
doaj +1 more source
Resumen: Introducción y objetivos: La terapia neoadyuvante en el cáncer de recto se asocia con una disminución del tamaño tumoral y es la indicación terapéutica para pacientes con tumores T3, T4 o con compromiso ganglionar.
L.J. Palacios-Fuenmayor +7 more
doaj +1 more source
SARS-CoV-2 Spike Antibody Levels Trend among Sinopharm Vaccinated People
None
Umar Saeed +3 more
doaj +1 more source
Introduction and aims: Neoadjuvant therapy in rectal cancer is associated with a decrease in tumor size and is the therapeutic indication for patients with T3 or T4 tumors or lymph node involvement.
L.J. Palacios-Fuenmayor +7 more
doaj +1 more source

