Results 91 to 100 of about 9,785 (196)

Upregulated CEMIP promotes intervertebral disc degeneration via AP‐1‐mediated change in chromatin accessibility

open access: yesClinical and Translational Medicine
Background Intervertebral disc degeneration (IDD), a chronic and multifactorial skeletal disorder, is the primary cause of low back pain. It results in reduced disc height and nucleus pulposus hydration due to proteoglycan loss and nucleus pulposus cells
Shibin Shu   +10 more
doaj   +1 more source

Unraveling the mechanisms of intervertebral disc degeneration: an exploration of the p38 MAPK signaling pathway

open access: yesFrontiers in Cell and Developmental Biology
Intervertebral disc (IVD) degeneration (IDD) is a worldwide spinal degenerative disease. Low back pain (LBP) is frequently caused by a variety of conditions brought on by IDD, including IVD herniation and spinal stenosis, etc.
Xingmin Zhang   +20 more
doaj   +1 more source

The Differences on the Fatty Infiltration of Paraspinal Muscles between Single‐ and Multiple‐level Intervertebral Disc Degeneration in Patients with Lumbar Disc Herniation

open access: yesOrthopaedic Surgery
Objective Multiple‐level Intervertebral disc degeneration (IDD) in patients with lumbar disc herniation (LDH) is related to postoperative re‐herniation and low back pain.
Minjie Shen   +6 more
doaj   +1 more source

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