Results 101 to 110 of about 9,828 (205)

Neurofilament Light Chain (Nfl) Level in Serum as a Suitable In Vivo Biomarker for Axonal Damage in a Murine Viral Model of Multiple Sclerosis

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Neurofilament light chain (Nfl) is a protein of the cytoskeleton predominantly found in large calibre myelinated axons and a suitable in vivo biomarker for monitoring neurodegenerative processes. Axonal damage results in Nfl release into the cerebrospinal fluid and the blood stream.
A. Segna   +8 more
wiley   +1 more source

PbrIDD2‐PbrAPX14 Module Functions in the Ethylene‐Mediated Ripening and Senescence Process of Pear Fruit

open access: yesPlant Biotechnology Journal, Volume 24, Issue 8, Page 4878-4896, August 2026.
ABSTRACT Endogenous H2O2 participated in the ethylene‐dependent ripening and senescence process of horticultural fruit as a secondary messenger; however, the molecular mechanism beneath such a phenomenon has not been fully clarified until recently. By a conjoint analysis of metabolite, enzyme activities, gene expression profiles in AsA‐GSH cycle of ...
Libin Wang   +12 more
wiley   +1 more source

PDE4B promotes ferroptosis in nucleus pulposus cells and is involved in intervertebral disc degeneration

open access: yesScientific Reports
Intervertebral Disc degeneration (IDD) is one of the leading causes of disability, and current therapies are ineffective. Phosphodiesterase 4B (PDE4B) plays an essential role in regulating the activation of nuclear factor E2-related factor 2 (Nrf2 ...
Weixing Xu   +6 more
doaj   +1 more source

The Differences on the Fatty Infiltration of Paraspinal Muscles between Single‐ and Multiple‐level Intervertebral Disc Degeneration in Patients with Lumbar Disc Herniation

open access: yesOrthopaedic Surgery
Objective Multiple‐level Intervertebral disc degeneration (IDD) in patients with lumbar disc herniation (LDH) is related to postoperative re‐herniation and low back pain.
Minjie Shen   +6 more
doaj   +1 more source

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