Results 121 to 130 of about 56,938 (262)

Antiviral Therapy and Post‐Resection Outcomes in Patients With Hepatitis B Virus‐Related Hepatocellular Carcinoma

Alimentary Pharmacology &Therapeutics, EarlyView.
In 902 patients with HBV‐related HCC undergoing curative resection, antiviral regimens (ETV, TDF, TAF) showed comparable recurrence‐free survival. However, TDF was independently associated with improved overall survival compared with ETV. ABSTRACT Background & Aims The comparative outcomes of entecavir (ETV), tenofovir disoproxil fumarate (TDF), and ...
Jaehong Jeong, Jung Pyo Hong, Dong Yun Kim, Jae Seung Lee, Mi Na Kim, Seung Up Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Hye Won Lee   +10 more
wiley   +1 more source

A Perspective for Integrating Real-World Evidence Into the Investigational Device Exemption Study Design for Lumbar Total Joint Replacement. [PDF]

Int J Spine Surg
Maislin D, Kurtz SM, Spece H, Breno AJ, Hodges SD, Yarbrough RV.   +5 more
europepmc   +1 more source

The role of generative AI in collaborative problem‐solving of authentic challenges

British Journal of Educational Technology, EarlyView.
Abstract This study investigates undergraduate and postgraduate teamwork in a four‐week ‘Generative AI for Social Good’ hackathon, focusing on how students use GAI tools in authentic problem‐solving within their learning ecology. It examines the factors that foster productive collaboration and explores evidence of AI extending human cognition beyond ...
Nancy Law, Nan Wang, Ming Ma, Zhichun Liu, Leon Lei, Shuhui Feng, Xiao Hu, Jack Tsao   +7 more
wiley   +1 more source

Protective Effect of Idebenone Against UVB-Induced Photoaging in HaCaT Cells. [PDF]

Drug Des Devel Ther
Feng L, Tian L, Guo J, Zhang L, Wang P, Bu X.   +5 more
europepmc   +1 more source

Real‐world prevalence and prognostic significance of hepatotoxicity after chimeric antigen receptor T‐cell therapy

British Journal of Haematology, EarlyView.
In this real‐world cohort of 231 patients receiving chimeric antigen receptor (CAR) T‐cell therapy, hepatotoxicity occurred in 58% of patients, predominantly as transient transaminase elevations, and was not associated with impaired 12‐month overall survival (adjusted hazard ratio [HR] 1.18, 95% confidence interval [CI] 0.71–1.94).
Julius Hollnberger, Tim Richardson, Philipp Gödel, Joshua Leutiger, Jan Christoph Schumacher, Sophie Schiestel, Benedict Allhoff, Christof Scheid, Udo Holtick, Christoph Neumann‐Haefelin, Gabriel Allo, Philipp Kasper   +11 more
wiley   +1 more source

CAR T-cell expansion after idecabtagene vicleucel is a predictor of outcomes in multiple myeloma. [PDF]

Hemasphere
Ferment B, Ouedrani A, Talbot A, Mouri N, Zarnitzky P, Stammler R, Vaugeois T, Diep A, Harel S, Royer B, Theves F, Forgeard N, Allain V, Caillat-Zucman S, Arnulf B.   +14 more
europepmc   +1 more source

From the Individual to the Community: A Qualitative Exploration of Professional Perspectives on Community Well‐Being Dimensions in Gran Canaria

Child &Family Social Work, EarlyView.
ABSTRACT Despite the growing body of literature on community well‐being, limited studies have explored how social service professionals conceptualise community dimensions in archipelagic or island territories, where territorial inequalities and access barriers pose unique challenges. This study explores how professionals from the Public Social Services
Jonay Del Pino García, Juan Carlos Martín Quintana, Carmen Delia Díaz Bolaños   +2 more
wiley   +1 more source

Real-World Experience with Approved CAR T-Cell Therapies Ciltacabtagene Autoleucel and Idecabtagene Vicleucel in 1272 Relapsed/Refractory Multiple Myeloma Patients. [PDF]

Cancers (Basel)
Filippatos C, Ntanasis-Stathopoulos I, Briasoulis A, Malandrakis P, Terpos E, Gavriatopoulou M.   +5 more
europepmc   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

Cell Proliferation, EarlyView.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang, Tan Li, Ping He, Zhijie Zhao, Shenglong Li, Liming Wang   +5 more
wiley   +1 more source

Impedimetric Analysis of the Photocatalysis-Assisted Response of Patterned TiO₂|ITO Electrodes Exposed to Artificial Sweat. [PDF]

Sensors (Basel)
Stefanov BI, Mateev VM, Tzaneva BR, Iliev IT.   +3 more
europepmc   +1 more source