Extramedullary Disease—Achilles Heel in Myeloma?
ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar +7 more
wiley +1 more source
From Trials to Practice: A 2025 Review of Idecabtagene Vicleucel and Ciltacabtagene Autoleucel Efficacy Across Clinical Studies and Real-World Evidence. [PDF]
Pleitez HG +5 more
europepmc +1 more source
Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man +7 more
wiley +1 more source
<i>In situ</i> reprogramming of fibroblasts into antigen-presenting pseudo-dendritic cells via IFN-β-engineered protoplast-derived exosomes delivered by microneedle arrays to enhance adaptive immunity. [PDF]
Yin Y +5 more
europepmc +1 more source
ABSTRACT Contemporary societies face slow‐burning crises – such as antimicrobial resistance (AMR) – that demand sustained responses from national governments but often elicit uneven action. Policy implementation, public health, and creeping crisis literatures have each proposed factors to explain why governments vary in their responses.
Nicholas Olczak, Mark Rhinard
wiley +1 more source
Extensive Uterine Necrosis and Peritonitis Following Clandestine Abortion Attempt: A Case Report. [PDF]
Soumana Diaouga H +5 more
europepmc +1 more source
“You Are Safe Now”: Migrant Youth Constructions of Safety and Schooling in the U.S.
ABSTRACT Drawing on multisited ethnographic research with migrant families from Brazil, El Salvador, Guatemala, and Honduras who were detained, separated, or endured prolonged transit due to US immigration policies, we articulate how ideas of “relational safety” are situated in relationships with people, place, and time. Contrasting abundant literature
Michelle J. Bellino, Gabrielle Oliveira
wiley +1 more source
A novel approach to promote upper-limb motor recovery in stroke survivors using assistive myoelectric control and adaptive visual feedback in virtual reality. [PDF]
Nocilli M, d'Avella A, Berger DJ.
europepmc +1 more source
Trading Zones Between Thick and Thin: Anthropological Description as Scaffold or Mosaic
ABSTRACT Referring to the work of historian of science Peter Galison, I argue that anthropology requires thin description as an essential counterpart for thick description. Thin accounts provide the scaffolding within which thick descriptions sit. Galison uses the idea of a “trading zone” connecting different communities who, despite their differences (
David Zeitlyn
wiley +1 more source
Different nucleos(t)ide analogs in resected hepatitis B virus-associated hepatocellular carcinoma: a systematic review. [PDF]
Qiu H, Zhang Y, Xu F, Xue S.
europepmc +1 more source

