Results 161 to 170 of about 4,737,123 (357)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

"Bangladesh is associated with the idea of resilience and the idea of a quiet revolution" - Shahpar Selim

, 2018
Following the 'Idea of Bangladesh' panel, forming part of the first LSE-UC Berkeley Summit, panellist Shahpar Selim spoke to Rebecca Bowers about the current greening initiatives taking place in garment factories across Bangladesh, and the potential to ...
Selim, Shahpar, Bowers, Rebecca
core  

Multidisciplinary approach to reducing falls for people with dementia on an older adult mental health ward. [PDF]

BMJ Open Qual
Sorlie C, Shields G, Connellan T, Addo N, Aurelio M.   +4 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

The Idea of Waste: On the Limits of Human Life

An exploration of both the reality and the spectre of waste throughout history. The Idea of Waste starts with the premise that waste is inevitable in human society.
Scanlan, John
core  

Main idea

, 2008
The main idea of this project was to create a text-to-speech synthesizer for minority languages, for which no commercial speech synthesizer software is available yet, e.g., Swiss German. Other applications include societies with a high analphabetism rate.
Implemented Stefan Marti, Opensource Speechsynth, Original Idea Deb Roy, Stefan Marti   +3 more
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Understanding inclusion, diversity, equity, and accessibility in a distributed data network: environmental scan within health data research network Canada. [PDF]

Int J Popul Data Sci
Freier A, Bowler L, Owczar H, Gogovor A, Pandy M, Riley J, Stirling M, Duris J, McGrail K, Nickel NC.   +9 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source