Results 51 to 60 of about 1,879,484 (310)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

ISLAM, HAK DAN KESEHATAN REPRODUKSI

open access: yesKomunika, 2015
Islam is often preceived as a religion that give lack attention to the rights of reproduction for women. Islam is considered as religion that views reproduction as women’s duty and never views women’s rights in relation to reproduction.
Waliko Waliko
doaj   +1 more source

Addressing the Relationship between Power, State and Society in Pre-Modern Iran [PDF]

open access: yesدولت‌پژوهی, 2019
This article, using the method of historical sociology and the sociology of knowledge, attempts to address the power relations between society and government in Iran before the emergence of the Pahlavi state.
Mahdi Abbasi Shahkooh
doaj   +1 more source

Ideal Prima Dan Ideal Maksimal Pada Gelanggang Polinomial [PDF]

open access: yes, 2014
Teori gelanggang merupakan salah satu bagian di matematika aljabar yang berkembang pesat saat ini. Dari suatu gelanggang R dapat dibentuk gelanggang baru R[x] yang disebut dengan gelanggang polinomial.
Khariani, Qharnida
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

El vértigo de la filosofía

open access: yesTheoría Revista del Colegio de Filosofía, 2010
Este ensayo es una interpretación de Filosofía del futuro de Eugenio Trías como una propuesta de pensamiento trágico contemporáneo. Para ello, el autor, amparándose en la noción de viaje trágico, desarrolla la concepción del devenir como reiteración ...
Crescenciano Grave
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Idealizations and ideal policing

open access: yesPhilosophers' Imprint, 2022
Political philosophy often focuses on “major institutions” that make up the “basic structure” of society. These include political, economic, and social institutions. In this paper I argue first that policing plays a substantial role in generating the kinds of inequalities and problems that are concerns of social or structural justice, and therefore ...
openaire   +1 more source

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