Results 61 to 70 of about 6,589,637 (292)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The study examines the creative process using the logical and methodological analysis of Plato’s concepts. It presents the modern scientific research related directly or indirectly to his philosophical views (the structural analogy method, the theory of ...
Anatoliy Stoletov
doaj +1 more source
Non-Euclidean ideal spectrometer
We describe the mathematical scheme for an anomaly-free ideal spectrometer, based on a 2-dimensional plane medium with conical regions of bounded slope.
Earp, Henrique N. Sá +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Desilusão: Impasses Clínicos e Políticos diante dos Dilemas de nosso Tempo
Acontecimentos sociais e políticos, nacionais e internacionais, têm abalado nosso cotidiano. Conquistas que pareciam sedimentadas na direção da democracia e nos temas relativos aos direitos humanos, conquistas sociais e considerações éticas na vida ...
Miriam Debieux Rosa +2 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Números y significaciones. La idealidad en la fenomenología incipiente de Husserl
La reflexión sobre los números y las significaciones es una buena muestra de cómo la fenomenología incipiente se sitúa en el terreno de la lógica pura. El artículo plantea que, para trazar una reflexión que no rasgue la personalidad filosófica de Husserl,
José Manuel Chillón
doaj +1 more source
Residuated Lattices with Noetherian Spectrum
In this paper, we characterize residuated lattices for which the topological space of prime ideals is a Noetherian space. The notion of i-Noetherian residuated lattice is introduced and related properties are investigated.
Dana Piciu, Diana Savin
doaj +1 more source
Invariance of Ideal Limit Points
Let $\mathcal{I}$ be an analytic P-ideal [respectively, a summable ideal] on the positive integers and let $(x_n)$ be a sequence taking values in a metric space $X$.
Leonetti, Paolo
core +1 more source
Bayesianism for Non-ideal Agents [PDF]
Orthodox Bayesianism is a highly idealized theory of how we ought to live our epistemic lives. One of the most widely discussed idealizations is that of logical omniscience: the assumption that an agent’s degrees of belief must be probabilistically ...
Bjerring, Jens Christian +1 more
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