Results 81 to 90 of about 6,589,637 (292)

Effects of Body Shape on Literal Objectification: When Ideal May Be Less Than Ideal [PDF]

open access: yes, 2018
Objectification, or the tendency to adopt an externalized view of self/other, is a ubiquitous process disproportionately affecting women (Fredrickson & Roberts, 1997).
Dunn, Jamie   +8 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Idealizations and ideal policing

open access: yesPhilosophers' Imprint, 2022
Political philosophy often focuses on “major institutions” that make up the “basic structure” of society. These include political, economic, and social institutions. In this paper I argue first that policing plays a substantial role in generating the kinds of inequalities and problems that are concerns of social or structural justice, and therefore ...
openaire   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Twenty-eight new and significant departmental reptile records for Paraguay

open access: yesActa Zoológica Lilloana
Twenty-eight new distribution records are reported for twenty-seven species of Paraguayan reptiles. Ten of these species are considered threatened at the national level (6 EN, 2 VU, 2 DD).
Paul Smith   +14 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Dostoevsky’s Ideal Man

open access: yes, 2015
This paper aimed to provide a comprehensive examination of the ideal Dostoevsky human being. Through comparison of various characters and concepts found in his texts, a kenotic individual, one who is undifferentiated in their love for all of God\u27s ...
Eppler, Paul A.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Levinson on the Aesthetic Ideal [PDF]

open access: yes, 2013
In “Artistic Worth and Personal Taste,” Jerrold Levinson develops a problem for those who think we should strive to be “ideal critics” in our aesthetic lives. He then offers several solutions to this problem.
Riggle, Nicholas
core  

On the Frohman Kania-Bartoszynska ideal

open access: yes, 2004
The Frohman Kania-Bartoszynska ideal is an invariant associated to a 3-manifold with boundary and a prime p >3. We give some estimates of this ideal.
Gilmer, Patrick M.
core   +4 more sources

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