Results 91 to 100 of about 6,589,637 (292)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Nonrelativisitic Ideal Gasses and Lorentz Violations

, 2004
We develop statistical mechanics for a nonrelativisitic ideal gas in the presence of Lorentz violating background fields. The analysis is performed using the Standard-Model Extension (SME). We derive the corresponding laws of thermodynamics and find that,
Colladay, Don, McDonald, Patrick
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

La educación y el sentido de la vida

Márgenes
En la actualidad, la sociedad se encuentra inmersa en una fascinación tecnológica que transforma la experiencia humana. El individuo contemporáneo es digital y transhumano, buscando conexión virtual, pero careciendo de contacto humano real.
Ricardo Orellana
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A COVID‐19 rapid antigen test employing upconversion nanoparticles

Smart Molecules
The COVID‐19 pandemic has underscored the critical need for rapid and accurate diagnostic tools. Current methods, including Polymerase Chain Reaction and rapid antigen tests (RAT), have limitations in speed, sensitivity, and the requirement for ...
Le Zhang, Jiajia Zhou, Olga Shimoni, Shihui Wen, Amani Alghalayini, Yuan Liu, Meysam Rezaeishahmirzadi, Jiayan Liao, Mahnaz Maddahfar, Roger Hunt, Murdo Black, Matt D. Johansen, Phil M. Hansbro, Lin Zhang, Martina Stenzel, Majid Warkiani, Stella M. Valenzuela, Dayong Jin   +17 more
doaj   +1 more source

LE CORPS FÉMININ ET SES FLUCTUATIONS DANS LES FLEURS DU MAL ET PETITS POÈMES EN PROSE DE CHARLES BAUDELAIRE [PDF]

Studii si Cercetari Filologice: Seria Limbi Romanice, 2020
Animée d’un souffle splénétique, l’œuvre baudelairienne raconte le corps féminin dans ses multiples fluctuations, partant du corps idéalisé pour sa beauté insolite, jusqu’à sa désacralisation par la souillure du désir charnel et l’emprise du temps.
Saadia RAHALI
doaj  

Ideal codes over separable ring extensions [PDF]

, 2014
This paper investigates the application of the theoretical algebraic notion of a separable ring extension, in the realm of cyclic convolutional codes or, more generally, ideal codes.
Gómez-Torrecillas, José, Lobillo, F. J., Navarro, Gabriel   +2 more
core  

Ideal Stabilization

2011 IEEE International Conference on Advanced Information Networking and Applications, 2011
We define and explore the concept of ideal stabilization. The program is ideally stabilizing if its every state is legitimate. Ideal stabilization allows the specification designer to prescribe with arbitrary degree of precision not only the fault-free program behavior but also its recovery operation.
Nesterenko, Mikhail, Tixeuil, Sébastien
openaire   +4 more sources