Results 101 to 110 of about 2,185,448 (315)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Rings all of whose additive group endomorphisms are left multiplications

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1984
Motivated by Cauchy's functional equation f(x+y)=f(x)+f(y), we study in §1 special rings, namely, rings for which every endomorphism f of their additive group is of the form f(x)≡ax. In §2 we generalize to R algebras (R a fixed commutative ring) and give
Michael I. Rosen, Oved shisha
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

A note on the zero divisor graph of a lattice [PDF]

open access: yesTransactions on Combinatorics, 2014
Let $L$ be a lattice with the least element $0$. An element $xin L$ is a zero divisor if $xwedge y=0$ for some $yin L^*=Lsetminus left{0right}$. The set of all zero divisors is denoted by $Z(L)$.
T. Tamizh Chelvam , S. Nithya
doaj  

Massenbverband der Ideal-Imperial-Bügelkohlen K.Pechtner, Nürnberg,Teleph.7145

open access: yes
MASSENBVERBAND DER IDEAL-IMPERIAL-BÜGELKOHLEN K.PECHTNER, NÜRNBERG,TELEPH.7145 Massenbverband der Ideal-Imperial-Bügelkohlen K.Pechtner, Nürnberg,Teleph.7145 ( -
Massenbverband der Ideal-Imperial-Bügelkohlen K.Pechtner, Nürnberg
core  

THE ALMOST IDEAL SUPPLY SYSTEM AND AGRICULTURAL PRODUCTION IN THE UNITED STATES [PDF]

open access: yes
This paper estimates an Almost Ideal Supply System using aggregate U.S. agricultural data. Share equations derived from an indirect production function yield elasticities that are consistent with production theory.
Hilmer, Christiana E., Holt, Matthew T.
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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