Results 151 to 160 of about 13,708,981 (254)

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Predicting Single‐Cell Perturbation Responses Across Biological Contexts With a Deep Generative Model Integrating Optimal Transport

Advanced Science, EarlyView.
Single‐cell perturbation responses are predicted across held‐out biological contexts using scPILOT, a query‐conditioned two‐stage latent response‐transfer framework. A shared latent representation supports cell‐level response estimation by latent optimal transport, followed by Leiden‐localized query‐specific transfer and adaptive weighting.
Jialiang Wang, Ziqi Liu, Zhengqian Zhang, Yikun Cao, Junjun Ren, Peng Cheng, Jingjing Tian, Lingyun Xie, Xin Lu, Zhanwei Du, Yongzhuang Liu   +10 more
wiley   +1 more source

Cardiovascular Health Metrics Differ Between Individuals With and Without Cancer.

Although individuals with cancer experience high rates of cardiovascular morbidity, there are limited data on the potential differences in cardiovascular health (CVH) metrics between individuals with and without cancer.
Menezes, Miguel Nobre, Fiuza, Manuela, Thavendiranathan, Paaladinesh, Parwani, Purvi, Ng, Cheng Han, Abramov, Dmitry, Kobo, Ofer, Mamas, Mamas A, Chew, Nicholas W S   +8 more
core   +1 more source

Association between Life’s Simple 7 and Menopause in a Community-based Population

Journal of Medical Sciences
Background: In 2010, the American Heart Association defined a new concept of ideal cardiovascular health (CVH) called Life’s Simple 7, which comprises seven parts, including smoking status (nonsmoking), body mass index (BMI) (
Wen-Chung Lu, Yuan-Ping Chao, Yung-Wen Cheng, Zhe-Yu Yang, Jun-Wei Huang, Tao-Chun Peng   +5 more
doaj   +1 more source

Total urinary polyphenols and ideal cardiovascular health metrics in Spanish adolescents enrolled in the SI Program: a cross-sectional study. [PDF]

Sci Rep, 2022
Laveriano-Santos EP, Arancibia-Riveros C, Parilli-Moser I, Ramírez-Garza SL, Tresserra-Rimbau A, Ruiz-León AM, Estruch R, Bodega P, de Miguel M, de Cos-Gandoy A, Carral V, Santos-Beneit G, Fernández-Alvira JM, Fernández-Jiménez R, Lamuela-Raventós RM.   +14 more
europepmc   +1 more source

MXene‐Based Room‐Temperature NO2 Gas Sensors: A Meta‐Analysis

Advanced Science, EarlyView.
This study presents the first comprehensive meta‐analysis of MXene‐based NO2 sensors, decoding 32 study characteristics across 61 peer‐reviewed studies. By isolating materials chemistry as the primary performance driver over device‐level parameters, the authors establish a methodological blueprint and a predictive structure–function map to accelerate ...
Alexander Khort, Jerome Geyer‐Klingeberg, Andreas Rathgeber, Suelen Barg   +3 more
wiley   +1 more source

Association of sarcopenia with ideal cardiovascular health metrics among US adults: a cross-sectional study of NHANES data from 2011 to 2018. [PDF]

BMJ Open, 2022
Chen W, Shi S, Jiang Y, Chen K, Liao Y, Huang R, Huang K.   +6 more
europepmc   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

Advanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen, Ying Ma, Lixuan Huang, Xin Chen, Fanliang Kong, Zhenzhou Qian, Mingyue Guan, Xinlin Wang, Yanyan Yang, Shasha Zhang, Peng Li, Renjie Chai   +11 more
wiley   +1 more source

Corrigendum: Ideal Cardiovascular Health Metrics and Incidence of Ischemic Stroke Among Hypertensive Patients: A Prospective Cohort Study. [PDF]

Front Cardiovasc Med, 2021
Ying Y, Lin S, Kong F, Li Y, Xu S, Liang X, Wang C, Han L.   +7 more
europepmc   +1 more source

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

Advanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li, Kai Su, Ruiwei Hu, Ke Gao, Yuanjie Liu, Lu Zhang, Ningke Fan, Yirong Chen, Wei Cheng, Shijia Ding, Haiping Wu   +10 more
wiley   +1 more source