Results 111 to 120 of about 944,351 (358)

Pragmatist Ethics and Climate Change [preprint] [PDF]

open access: yes, 2020
This chapter explores some features of pragmatic pluralism as an ethical perspective on climate change. It is inspired in part by Andrew Light’s work on climate diplomacy as U.S.
Fesmire, Steven
core  

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

open access: yesAdvanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams   +7 more
wiley   +1 more source

Compassion or Renunciation? “That” is the question of Schopenhauer’s ethics

open access: yesEnrahonar: Quaderns de Filosofia, 2015
The traditional view of Schopenhauer’s ethical thought is to see renunciation from the will-to-life as the truest, most ethical response to a world such as ours in which suffering is tremendous, endemic, and unredeemed.
Sandra Shapshay, Tristan Ferrell
doaj   +1 more source

High‐Entropy Alloy Design Toward Cobalt Substitution for High Hardness and Low Wear Rate Using X–Cr–Fe–Mn–Ni System

open access: yesAdvanced Engineering Materials, EarlyView.
This study explores the replacement of cobalt using the high‐entropy alloy design strategy for wear‐resistant components operating at high temperatures. Starting from the Cantor alloy, cobalt is substituted with Cu, Al, V, or Mo. Metallurgical and tribological analyses reveal that aluminum, vanadium, and molybdenum effectively strengthen the developed ...
Rafaël Jénot   +5 more
wiley   +1 more source

Precise Quantification of Angiogenesis in 3D Biomaterials Using in Vitro CAM Models: Enhancing 3Rs in Research and Minimizing in Vivo Dependency

open access: yesAdvanced Functional Materials, EarlyView.
The study develops elastin–fibrin scaffolds and evaluates angiogenesis using the chorioallantoic membrane (CAM) model. Advanced imaging with confocal microscopy and Indocyanine Green dye enables precise 3D quantification of vascular networks. Findings demonstrate superior microvessel visualization compared to micro‐CT using Microfil and Optiray 350 ...
Ece Melis Er   +8 more
wiley   +1 more source

Functional Constitutivism’s Misunderstood Resources: A Limited Defense of Smith’s Constitutivism [PDF]

open access: yes, 2019
In recent work, Michael Smith argues that particular desires are constitutive of ideal agency and draws on his dispositional account of reasons to establish the normative significance of those desires.
Lindeman, Kathryn
core  

Micropatterned Biphasic Printed Electrodes for High‐Fidelity on‐Skin Bioelectronics

open access: yesAdvanced Functional Materials, EarlyView.
Micropatterned biphasic printed electrodes achieve unprecedented skin conformity and low impedance by combining liquid‐metal droplets with microstructured 3D lattices. This scalable approach enables high‐fidelity detection of ECG, EMG, and EEG signals, including alpha rhythms from the forehead, with long‐term comfort and stability.
Manuel Reis Carneiro   +4 more
wiley   +1 more source

Geoengineering and Non-Ideal Theory [PDF]

open access: yes, 2016
The strongest arguments for the permissibility of geoengineering (also known as climate engineering) rely implicitly on non-ideal theory—roughly, the theory of justice as applied to situations of partial compliance with principles of ideal justice. In an
Morrow, David R., Svoboda, Toby
core  

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

open access: yesAdvanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila   +7 more
wiley   +1 more source

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