Results 151 to 160 of about 2,399,806 (369)

Covalent Binding of Dexamethasone to Polyimide Improves Biocompatibility of Neural Implantable Devices

open access: yesAdvanced Healthcare Materials, EarlyView.
The covalent binding of dexamethasone to the surface of polyimide represents the electrically inert part of implantable intraneural devices. This ensures a sustained release of the drug for 9 weeks. In vitro and in vivo tests confirm the reduction of the foreign body reactions and the improved biocompatibility of dexamethasone functionalized polyimide.
Giulia Turrin   +19 more
wiley   +1 more source

Mandate of establishing an ethical review committee

open access: yesJournal of Bahria University Medical and Dental College, 2014
The National Bioethics Committee (NBC) was approved by the Government of Pakistan in 2004. Its basic mandate is to “promote and facilitate ethical health services delivery and health related research.
Ambreen Usmani   +2 more
doaj  

High‐Throughput Encapsulation of Stem Cells: Characterizing Dynamic Culture Variability With a Millifluidic Approach

open access: yesAdvanced Healthcare Materials, EarlyView.
A high throughput millifluidic encapsulation platform is engineered and standardized. The system's output allows the monitoring of cell expansion in strong dynamic conditions. High polymer crosslinking leads to higher cell proliferation and lower cell growth on microgel's surface.
Oscar Fabian García‐Aponte   +6 more
wiley   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis   +5 more
wiley   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren   +13 more
wiley   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han   +7 more
wiley   +1 more source

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