Results 41 to 50 of about 269,412 (259)

Utopia as the Gift of Ethical Genius: Ernst Cassirer’s Theory of Utopia

Eidos. A Journal for Philosophy of Culture, 2018
In this essay, I explore Cassirer’s brief discussion of utopia in An Essay on Man, as likely built upon Kant’s theory of genius as from the Critique of Judgment.
Eli Kramer
doaj   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Ideal cardiovascular health status and preeclampsia: a cohort study [PDF]

Revista Brasileira de Enfermagem
Objectives: to evaluate the association between preeclampsia and the cardiovascular health status of pregnant women. Methods: we conducted a cohort study with 101 pregnant women, following ethical principles and approved by a research ethics committee ...
João Joadson Duarte Teixeira, Bárbara Brandão Lopes, Maria das Graças da Silva Guerreiro, Nádya dos Santos Moura, Lúcia de Fátima da Silva, Rebeca Silveira Rocha, Dafne Paiva Rodrigues, Mônica Oliveira Batista Oriá   +7 more
doaj   +1 more source

Teaching Ethics of Technology based on Razavi Teachings in the Context of Virtual Social Networks [PDF]

International Multidisciplinary Journal of Pure Life, 2018
One of the most widely used areas of ethics is ethics in technology-based environments or information technology ethics, which has become a necessity in recent years with the advent of virtual social networks. This research intends to apply the ethics of
Rahim Moradi (Iran), Dr. Ismaeil Zareei Zavaraki (Iran)   +1 more
doaj   +1 more source

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

ETICA AUTONOMIEI ŞI ETICA AUTENTICITĂŢII. AFINITĂŢI, DISTINCŢII ŞI OPOZIŢII

Studia Universitatis Moldaviae: Stiinte Umanistice, 2019
Atât etica autonomiei, cât şi etica autenticităţii pot fi sintetizate prin aceeaşi exigenţă metaforică de a deveni propriul tău stăpân. Aceasta nu este doar o simplă coincidenţă.
Daniel NICA
doaj  

Hip Morphology–Based Osteoarthritis Risk Prediction Models: Development and External Validation Using Individual Participant Data From the World COACH Consortium

Arthritis Care &Research, EarlyView.
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Jinchi Tang, Harbeer Ahedi, Nigel K. Arden, Sita M. A. Bierma‐Zeinstra, Cindy G. Boer, Flavia M. Cicuttini, Timothy F. Cootes, David T. Felson, Willem Paul Gielis, Joshua Heerey, Graeme Jones, Stefan Kluzek, Nancy E. Lane, Claudia Lindner, Joyce B. J. van Meurs, Andrea Mosler, Amanda E. Nelson, Michael C. Nevitt, Edwin H. Oei, Jos Runhaar, Harrie Weinans, Jesse H. Krijthe, Rintje Agricola   +26 more
wiley   +1 more source

Etika Politik dalam Perspektif al-Mawardi

Tsaqafah, 2018
In this era, political ethics seems to be no longer valid, but it is almost disappeared. The reality shows that politics is a place for fighting of powers and interests, so that there is a general tendency to justify any means to achieve goals. Political
Rashda Diana, Siswanto Masruri, Surwandono Surwandono   +2 more
doaj   +1 more source