Results 51 to 60 of about 288,716 (309)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Bioregionalism: Practical Environmental Ethics with an Underlying Pragmatic Ideal

open access: yesProblemy Ekorozwoju, 2018
The theories of environmental ethics battle about appropriate value of nature and consequently the appropriate human attitude towards nature. However, they are unable to influence actual human behavior towards nature. So what we need here is not another
Ipsita Sarkar, Ajit Behura
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Is virtue ethics self-effacing?

open access: yes, 2010
Thomas Hurka, Simon Keller, and Julia Annas have recently argued that virtue ethics is self-effacing. I contend that these arguments are rooted in a mistaken understanding of the role that ideal agency and agent flourishing (should) play in virtue ethics.
Glen Pettigrove, Pettigrove, Glen
core   +1 more source

Ethical Idealism, Technology and Practice: a Manifesto

open access: yesPhilosophy & Technology, 2022
Technology has become one of the main channels through which people engage in most of their everyday activities. When working, learning, or socializing, the affordances created by technological tools determine the way in which users interact with one another and their environment, thus favoring certain actions and behaviors, while discouraging others ...
openaire   +4 more sources

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Beyond the Manager’s Moral Dilemma: Rethinking the ‘Ideal-Type’ Business Ethics Case

open access: yes, 2010
Case teaching occupies a central place in the history of business education and in recognition of its significance, the Journal of Business Ethics recently created a new section for cases.
Bridgman, Todd   +2 more
core   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

How to think about health promotion ethics [PDF]

open access: yes, 2012
Health promotion ethics is moral deliberation about health promotion and its prac­ tice. Although academics and practitioners have been writing about ethics, and especially values, in health promotion for decades, health promotion ethics is now
John P. Allegrante   +5 more
core   +1 more source

Karakter Pendidik dan Peserta Didik

open access: yesINSANIA: Jurnal Pemikiran Alternatif Kependidikan, 2018
: Indonesia faces many problems of education that should be understood and soived wiseiy. One ofthe ways to do so is by utitizing the classical thories and contextualizing them within lndonesian, global, and lslamic perspective.
Yahya Zahid
doaj   +3 more sources

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