Results 71 to 80 of about 288,716 (309)

Ideal cardiovascular health status and preeclampsia: a cohort study [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to evaluate the association between preeclampsia and the cardiovascular health status of pregnant women. Methods: we conducted a cohort study with 101 pregnant women, following ethical principles and approved by a research ethics committee ...
João Joadson Duarte Teixeira   +7 more
doaj   +1 more source

Business Ethics and Ideals

open access: yesBusiness Ethics Journal Review, 2014
John Hasnas (2013) argues for a “Principles Approach” to supplant normative theory and casuistry in business ethics pedagogy. This Commentary argues some normative theory ought still to have some place in business ethics education and that the problems Hasnas sees in business ethics pedagogy only tell half the story.
openaire   +3 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Intergenerational ethics and climate change [PDF]

open access: yes
Global climate change has important implications for the way in which benefits and burdens will be distributed amongst present and future generations.
Page, Edward
core  

The Ethics of Humanitarian Intervention

open access: yes
Few topics generate as much controversy and debate as armed humanitarian intervention. Military force involves death and destruction, as well as interfering in other countries’ domestic affairs.
Parry, Jonathan
core   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

Business ethics & collective responsibility

open access: yes, 2013
The idea that ‘business ethics’ picks out a distinct discipline within ethical theory is contentious; in particular, it is unclear why theoretical approaches to moral and political philosophy cannot satisfactorily address ethical concerns in the context ...
Dempsey, James A.
core  

Heidegger and environmental ethics [PDF]

open access: yes, 2001
This thesis presents an environmental ethic based on the philosophy of Martin Heidegger. Chapter One uses Heidegger's conception of 'dwelling' as the basis for a satisfying account of the 'otherness' or alterity of nature.
James, Simon Paul, James, S.P.
core  

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay   +13 more
wiley   +1 more source

Ethics and foreign policy : negotiation and invention [PDF]

open access: yes
To what extent can ethics and foreign policy be conceived as possible? Instead of answering within the implied dichotomy of possibility and impossibility, this thesis argues for a reconceptualisation of the dichotomy.
Bulley, Daniel
core  

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