Results 51 to 60 of about 2,399,806 (369)

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Adjusting the Ideal Islamic Religious Education Curriculum to the Development of AI-Based Technology

open access: yesProgresiva : Jurnal Pemikiran dan Pendidikan Islam
The development of technology is currently experiencing a very rapid development, one of which is the emergence of an innovation called AI (artificial intelligence). Islamic religious education indirectly gets an impact on the emergence of AI (artificial
Sari Hernawati   +2 more
semanticscholar   +1 more source

Who Cares? Care and the Ethical Self

open access: yesLes Ateliers de l’Ethique, 2015
Over three decades ago, Carol Gilligan’s seminal book In a Different Voice provided feminist theorists with a powerful new approach to address the shortcomings of traditional moral theories.
Monique Lanoix
doaj   +1 more source

Transovereignty: Separating Human Rights from Traditional Sovereignty and the Implications for the Ethics of International Law Practice [PDF]

open access: yes, 1993
Part I of this Article develops some necessary perspective on transovereignty and its importance to law and ethics by reflecting first on traditional sovereignty.
McNamee, Bernard L., Terrell, Timothy P.
core   +1 more source

Derivation of Morality from Prudence [PDF]

open access: yes, 2020
This chapter derives and refines a novel normative moral theory and descriptive theory of moral psychology--Rightness as Fairness--from the theory of prudence defended in Chapter 2.
Arvan, Marcus
core   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

The Problems of Teaching the Basics of Secular Ethics to Pedagogic Students

open access: yesОбразование и наука, 2015
The paper looks at the specialists training for teaching the Basics of Secular Ethics course in the secondary school. In author’s opinion, the above course is entitled to develop children’s moral consciousness.
L. V. Shcheglova
doaj   +1 more source

The Role of Compassion in Medical Ethics and Its Reintegration in Modern Practice [PDF]

open access: yes, 2019
Compassion has been an integral part of medical ethics since its origins, but as medicine progressed, compassion slowly disappeared from practice.
Borchers, Hannah E
core   +1 more source

Hegel and the Ethics of Brandom’s Metaphysics [PDF]

open access: yes, 2018
In order to develop his pragmatist and inferentialist framework, Robert Brandom appropriates, reconstructs and revises key themes in German Idealism such as the self-legislation of norms, the social institution of concepts and facts, a norm-oriented ...
Lewis, Jonathan
core   +2 more sources

Home - About - Disclaimer - Privacy